A New Hydroxyapatite/Glass Biphasic Material: In Vitro Bioactivity
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2002
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American Chemical Society
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Rámila, A., et al. «A New Hydroxyapatite/Glass Biphasic Material: In Vitro Bioactivity». Chemistry of Materials, vol. 14, n.o 6, junio de 2002, pp. 2439-43. DOI.org (Crossref), https://doi.org/10.1021/cm011165p
Abstract
A new biphasic material composed of hydroxyapatite and a bioactive glass has been synthesized. The starting materials were hydroxyapatite (HA), synthesized by a wet method, and gel obtained by a sol−gel method with composition in mol %, 55SiO2−41CaO−4P2O5 (55S), both prepared before the mixture. This mixture was performed mechanically and had a final ratio HA/55S glass of 80:20. In vitro assays of bioactivity were carried out to compare the behavior of the three materials. The biphasic material has shown good bioactivity, establishing that the addition of the bioactive glass to the hydroxyapatite accelerates the formation of a hydroxyapatite layer, enhancing the bioactivity of the synthetic HA.
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Se ha sintetizado un nuevo material bifásico compuesto por hidroxiapatita y un vidrio bioactivo. Los materiales de partida fueron hidroxiapatita (HA), sintetizada por un método húmedo, y vidrio obtenido por un método sol-gel con composición en mol %, 55SiO2-41CaO-4P2O5 (55S), ambos sintetizados antes de la mezcla. Esta mezcla se realizó mecánicamente y tuvo una proporción final HA/vidrio 55S de 80:20. Se realizaron ensayos in vitro de bioactividad para comparar el comportamiento de los tres materiales. El material bifásico ha mostrado una buena bioactividad, estableciéndose que la adición del vidrio bioactivo a la hidroxiapatita acelera la formación de una capa de hidroxiapatita, potenciando la bioactividad de la HA sintética.