Diurnal Triglyceridemia in Relation to Alcohol Intake in Men

dc.contributor.authorTorres do Rego, Ana
dc.contributor.authorKlop, Boudewijn
dc.contributor.authorBirnie, Erwin
dc.contributor.authorElte, Jan
dc.contributor.authorCachofeiro Ramos, María Victoria
dc.contributor.authorÁlvarez-Sala Walther, Luis Antonio
dc.contributor.authorCabezas, Manuel
dc.date.accessioned2023-06-19T13:44:31Z
dc.date.available2023-06-19T13:44:31Z
dc.date.issued2013-12-16
dc.description.abstractFasting and postprandial triglyceride concentrations largely depend on dietary and lifestyle factors. Alcohol intake is associated with triglycerides, but the effect of alcohol on diurnal triglyceridemia in a free living situation is unknown. During three days, 139 men (range: 18–80 years) measured their own capillary triglyceride (cTG) concentrations daily on six fixed time-points before and after meals, and the total daily alcohol intake was recorded. The impact of daily alcohol intake (none; low, <10 g/day; moderate, 10–30 g/day; high, >30 g/day) on diurnal triglyceridemia was analyzed by the incremental area under the cTG curve (∆cTG-AUC) reflecting the mean of the six different time-points. Fasting cTG were similar between the alcohol groups, but a trend of increased cTG was observed in men with moderate and high alcohol intake after dinner and at bedtime (p for trend <0.001) which persisted after adjustment for age, smoking and body mass index. The ∆cTG-AUC was significantly lower in males with low alcohol intake (3.0 ± 1.9 mmol·h/L) (n = 27) compared to males with no (7.0 ± 1.8 mmol·h/L) (n = 34), moderate (6.5 ± 1.8 mmol·h/L) (n = 54) or high alcohol intake (7.2 ± 2.2 mmol·h/L) (n = 24), when adjusted for age, smoking and body mass index (adjusted p value < 0.05). In males, low alcohol intake was associated with decreased diurnal triglyceridemia, whereas moderate and high alcohol intake was associated with increased triglycerides after dinner and at bed time.
dc.description.departmentDepto. de Fisiología
dc.description.departmentDepto. de Medicina
dc.description.facultyFac. de Medicina
dc.description.refereedTRUE
dc.description.sponsorshipInstituto de Salud Carlos III (ISCIII)
dc.description.statuspub
dc.eprint.idhttps://eprints.ucm.es/id/eprint/65900
dc.identifier.doi10.3390/nu5125114
dc.identifier.issn2072-6643
dc.identifier.officialurlhttps://doi.org/10.3390/nu5125114
dc.identifier.relatedurlhttps://www.mdpi.com/2072-6643/5/12/5114
dc.identifier.urihttps://hdl.handle.net/20.500.14352/34354
dc.issue.number12
dc.journal.titleNutrients
dc.language.isoeng
dc.page.final5126
dc.page.initial5114
dc.publisherMDPI
dc.relation.projectIDRD 12/0042/0033
dc.rightsAtribución 3.0 España
dc.rights.accessRightsopen access
dc.rights.urihttps://creativecommons.org/licenses/by/3.0/es/
dc.subject.keywordethanol
dc.subject.keywordlipemia
dc.subject.keywordpostprandial
dc.subject.keywordtriglyceride
dc.subject.ucmDietética y nutrición (Medicina)
dc.subject.unesco3206 Ciencias de la Nutrición
dc.titleDiurnal Triglyceridemia in Relation to Alcohol Intake in Men
dc.typejournal article
dc.volume.number5
dspace.entity.typePublication
relation.isAuthorOfPublication83b1b0b7-c61b-42a2-b795-9b0e1acefda4
relation.isAuthorOfPublicationebdaa257-c25c-4a84-85a7-fc55b3ff1aa3
relation.isAuthorOfPublication.latestForDiscoveryebdaa257-c25c-4a84-85a7-fc55b3ff1aa3
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