An Expedient Regio- and Diastereoselective Synthesis of Hybrid Frameworks with Embedded Spiro[9,10]dihydroanthracene [9,3′]-pyrrolidine and Spiro[oxindole-3,2′-pyrrolidine] Motifs via an Ionic Liquid-Mediated Multicomponent Reaction

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dc.contributor.authorArumugam, Natarajan
dc.contributor.authorAlmansour, Abdulrahman
dc.contributor.authorKumar, Raju
dc.contributor.authorMenéndez Ramos, José Carlos
dc.contributor.authorSultan, Mujeeb
dc.contributor.authorKarama, Usama
dc.contributor.authorGhabbour, Hazem
dc.contributor.authorFun, Hoong-Kun
dc.date.accessioned2023-06-18T06:06:43Z
dc.date.available2023-06-18T06:06:43Z
dc.date.issued2015-09-03
dc.description.abstractA series of hitherto unreported anthracene-embedded dispirooxindoles has been synthesized via a one-pot three-component 1,3-dipolar cycloaddition reaction of an azomethine ylide, generated in situ from the reaction of isatin and sarcosine to 10-benzylideneanthracen9(10H)-one as a dipolarophile in 1-butyl-3-methylimidazolium bromide([bmim]Br), an ionic liquid. This reaction proceeded regio- and diastereoselectively, in good to excellent yields.
dc.description.departmentDepto. de Química en Ciencias Farmacéuticas
dc.description.facultyFac. de Farmacia
dc.description.refereedTRUE
dc.description.sponsorshipDeanship of Scientific Research at King Saud University
dc.description.statuspub
dc.eprint.idhttps://eprints.ucm.es/id/eprint/69035
dc.identifier.doi10.3390/molecules200916142
dc.identifier.issn1420-3049
dc.identifier.officialurlhttps://doi.org/10.3390/molecules200916142
dc.identifier.relatedurlhttps://www.mdpi.com/1420-3049/20/9/16142
dc.identifier.urihttps://hdl.handle.net/20.500.14352/23898
dc.issue.number9
dc.journal.titleMolecules
dc.language.isoeng
dc.page.final16153
dc.page.initial16142
dc.publisherMDPI
dc.relation.projectIDRGP-VPP-026
dc.rightsAtribución 3.0 España
dc.rights.accessRightsopen access
dc.rights.urihttps://creativecommons.org/licenses/by/3.0/es/
dc.subject.cdu547
dc.subject.keywordmulticomponent reactions
dc.subject.keyword1
dc.subject.keyword3-dipolar cycloaddition reactions
dc.subject.keywordspirooxindoles
dc.subject.keywordspiropyrrolidines
dc.subject.keywordionic liquids
dc.subject.ucmQuímica orgánica (Farmacia)
dc.titleAn Expedient Regio- and Diastereoselective Synthesis of Hybrid Frameworks with Embedded Spiro[9,10]dihydroanthracene [9,3′]-pyrrolidine and Spiro[oxindole-3,2′-pyrrolidine] Motifs via an Ionic Liquid-Mediated Multicomponent Reaction
dc.typejournal article
dc.volume.number20
dspace.entity.typePublication
relation.isAuthorOfPublication4c8ca147-677d-4846-97b7-d4419662ff60
relation.isAuthorOfPublication.latestForDiscovery4c8ca147-677d-4846-97b7-d4419662ff60

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