Mesopic pupillary reflex in patients treated with fluoxetine

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dc.contributor.authorRodríguez Alonso, Xabier
dc.contributor.authorGutiérrez Jorrín, Sara Carmen
dc.contributor.authorBonnin Arias, Cristina Natalia
dc.contributor.authorRubio Corgo, Sandra
dc.contributor.authorArregui Olaizola, Carlota
dc.contributor.authorQuezada Sánchez, Johnny
dc.contributor.authorLópez-Ibor Alcocer, María Inés
dc.contributor.authorSánchez Ramos, Celia
dc.date.accessioned2024-07-03T16:54:32Z
dc.date.available2024-07-03T16:54:32Z
dc.date.issued2020-03-01
dc.descriptionTambién hay versión en español de la revista. En el repositorio Docta: https://hdl.handle.net/20.500.14352/6328 Acceso al texto completo en la web del editor
dc.description.abstractIntroduction: currently the treatment of mental illness by antidepressants is very frequent. Selective serotonin reuptake inhibitors are the most prescribed antidepressants worldwide and have been associated with alterations in accommodation or pupil. The objective of this study is to evaluate the effects of fluoxetine on the pupillary reflex and the accommodation in young population. Methodology: The study group included seven patients diagnosed with depression and treated with fluoxetine; 22 subjects were included as a control group. The pupillary reflexes and the accommodative state were evaluated using the Power Refractor II pupilometer. Five phases of 3 seconds each were measured. In phase 2 there was a glare with a white light. Results: For the pupil diameter, maximum and minimum values were obtained in the group of patients treated with fluoxetine than in the control in all the measurement phases. For the control group, a maximum pupillary contraction is observed in the glare phase, however, in the study group it is observed in the phase after glare. As for the accommodation, there are no significant differences between the two groups. Conclusions: In patients treated with fluoxetine there are pupillary alterations like a bigger pupillary diameters and slower pupillary contraction. The lack of conclusive results in terms of accommodation does not mean that there are no changes related to it, whose detection requires future studies with different methodologies and with a larger sample size.
dc.description.departmentDepto. de Optometría y Visión
dc.description.facultyFac. de Óptica y Optometría
dc.description.fundingtypePagado por el autor
dc.description.refereedTRUE
dc.description.statuspub
dc.identifier.citationRodríguez-Alonso, Xabier, et al. “Mesopic Pupillary Reflex in Patients Treated With Fluoxetine”. Actas Españolas De Psiquiatría, vol. 48, no. 2, Mar. 2020, pp. 47-53, https://actaspsiquiatria.es/index.php/actas/article/view/226.
dc.identifier.essn1578-2735
dc.identifier.issn1139-9287
dc.identifier.officialurlhttps://actaspsiquiatria.es/index.php/actas/article/view/226/300
dc.identifier.pmid32463910
dc.identifier.relatedurlhttps://actaspsiquiatria.es/index.php/actas/article/view/226
dc.identifier.relatedurlhttps://actaspsiquiatria.es/index.php/actas/article/view/226/302
dc.identifier.relatedurlhttps://hdl.handle.net/20.500.14352/6328
dc.identifier.urihttps://hdl.handle.net/20.500.14352/105582
dc.issue.number2
dc.journal.titleActas Españolas de Psiquiatría
dc.language.isoeng
dc.page.final53
dc.page.initial47
dc.publisherSTM editores
dc.rights.accessRightsrestricted access
dc.subject.cdu615.214.32:617.721.5
dc.subject.cdu612.84
dc.subject.cdu617.721.5
dc.subject.keywordMesopic Pupillary Reflex
dc.subject.keywordFluoxetine
dc.subject.keywordDepression
dc.subject.keywordVisual System
dc.subject.keywordPredictive Indicator
dc.subject.ucmÓptica y optometría
dc.subject.ucmPsiquiatría
dc.subject.ucmÓptica fisiológica
dc.subject.unesco3211 Psiquiatría
dc.subject.unesco2411.15 Fisiología de la Visión
dc.subject.unesco2209.15 Optometría
dc.titleMesopic pupillary reflex in patients treated with fluoxetine
dc.title.alternativeReflejo pupilar mesópico en pacientes tratados con fluoxetina
dc.typejournal article
dc.type.hasVersionVoR
dc.volume.number48
dspace.entity.typePublication
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