Regulation of neutrophilia by granulocyte colony-stimulating factor: a new cancer therapy that reversed a case of terminal hepatocellular carcinoma

Abstract

This work reports the possible cure of a 56-year-old patient with advanced hepatocarcinoma. Intense peritumoral neutrophilia was achieved by administering granulocyte colonystimulating factor (G-CSF), an experimental treatment based on the theory of universal tumour dynamics. After the first 8-week cycle of treatment, the patient’s α-fetoprotein (AFP) levels were reduced to normal and his general condition improved sufficiently to allow him to return to work. Following a second cycle of treatment, administered because of doubt regarding the tumoral or inflammatory nature of the now smaller liver mass, the patient’s AFP levels remained normal and he continued to enjoy good general health.