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HLA study in Mexico Nahua/Aztec Amerindians: Close relatedness to the ancient Central America ethnic groups

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dc.contributor.authorSuarez Trujillo, Fabio
dc.contributor.authorVargas Alarcon, Gilberto
dc.contributor.authorJuárez Martín-Delgado, Ignacio
dc.contributor.authorGil Martin, Roberto
dc.contributor.authorGranados, Julio
dc.contributor.authorVaquero Yuste, Christian
dc.contributor.authorMartín Villa, José Manuel
dc.contributor.authorArnaiz Villena, Antonio
dc.date.accessioned2024-01-10T11:57:28Z
dc.date.available2024-01-10T11:57:28Z
dc.date.issued2023-05
dc.description.abstractNahua population (also named Aztec or Mexica) was studied for HLA class II genes in a Mexican rural city (Santo Domingo Ocotitlan, Morelos State) belonging to the nowadays Náhuatl speaking areas in Mexico. The most frequent HLA class II alleles were typical Amerindian (HLA-DRB1*04:07, DQB1*03:01 DRB1*04:03 or DRB1*04:04) and also were some calculated extended haplotypes (HLA-DRB1*04:07-DQB1*03:02,DRB1*08:02-DQB1*04:02, or DRB1*10:01-DQB1*05:01 among others). When using HLA-DRB1 Neís genetic distances, our isolated Nahua population was found to be close to other Central America Amerindians like the ancient-established Mayans or Mixe. This may suggest that Nahuas origin was also from Central America. It contrasts to legend that assumes they came from the North, and they built the Aztec Empire after submitting Central America neighbouring ethnic groups before 1519 CE when Spaniards led by Hernán Cortés arrived to Mexico
dc.description.departmentDepto. de Inmunología, Oftalmología y ORL
dc.description.facultyFac. de Medicina
dc.description.refereedTRUE
dc.description.sponsorshipUnión Europea
dc.description.sponsorshipMinisterio de Ciencia y Universidades
dc.description.statuspub
dc.identifier.citationSuarez-Trujillo F, Vargas-Alarcon G, Juarez I, Gil-Martin R, Granados J, Vaquero-Yuste C, Martin-Villa JM, Arnaiz-Villena A. HLA study in Mexico Nahua/Aztec Amerindians: Close relatedness to the ancient Central America ethnic groups. Hum Immunol. 2023 May-Jul;84(5-7):313-314. doi: 10.1016/j.humimm.2023.03.004
dc.identifier.doi10.1016/j.humimm.2023.03.004
dc.identifier.issn0198-8859
dc.identifier.officialurlhttps://www.sciencedirect.com/science/article/pii/S0198885923000563?via%3Dihub
dc.identifier.relatedurlhttps://pubmed.ncbi.nlm.nih.gov/36973123/
dc.identifier.urihttps://hdl.handle.net/20.500.14352/92227
dc.issue.number5-7
dc.journal.titleHuman Immunology
dc.language.isoeng
dc.page.final314
dc.page.initial313
dc.publisherElsevier
dc.relation.projectIDinfo:eu-repo/grantAgreement/ISCIII/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016 (ISCIII)/PI18%2F00626/ES/HLA-G: CANCER GASTRICO Y SU EVOLUCION/
dc.relation.projectIDPI18/00721
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internationalen
dc.rights.accessRightsopen access
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject.cdu612.017
dc.subject.keywordAmerindians
dc.subject.keywordAztecEmpire
dc.subject.keywordAztecs
dc.subject.keywordHLA
dc.subject.keywordJaidukama
dc.subject.keywordMayas
dc.subject.keywordMazatecans
dc.subject.keywordMexicas
dc.subject.keywordMexico
dc.subject.keywordMixe
dc.subject.keywordNahuas
dc.subject.keywordNáhuatl
dc.subject.keywordTarahumara
dc.subject.keywordTotonacs
dc.subject.keywordZapotecans
dc.subject.ucmInmunología
dc.subject.unesco2412 Inmunología
dc.titleHLA study in Mexico Nahua/Aztec Amerindians: Close relatedness to the ancient Central America ethnic groups
dc.typejournal article
dc.type.hasVersionVoR
dc.volume.number84
dspace.entity.typePublication
relation.isAuthorOfPublication0894d58b-fe71-42aa-ad0a-19305823daa1
relation.isAuthorOfPublicationd6c35711-8ed5-412f-8345-8b8e3869353a
relation.isAuthorOfPublicationd2f85bbc-31c7-4587-8da2-1dc2a3e22d74
relation.isAuthorOfPublication.latestForDiscovery0894d58b-fe71-42aa-ad0a-19305823daa1

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