Presence of melatonin in human tears

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Carpena, Carlos
Concepción, Pablo
Díaz, Victor
García-García, Miguel
Jemnic, Nahla
Lledó, Victoria Eugenia
Martín, Marina
Pastrana, Cristina
Pelissier, Raquel
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Spanish General Council of Optometrists
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Open Access funded by Spanish General Council of Optometry
1. Stehle JH, Saade A, Rawashdeh O, et al. A survey of molecular details in the human pineal gland in the light of phylogeny, structure, function and chronobiological diseases. J Pineal Res. 2011;51:17---43. 2. Claustrat B, Leston J. Melatonin: physiological effects in humans. Neuro-Chirurgie. 2015;61:77---84. 3. Wiechmann AF, Summers JA. Circadian rhythms in the eye: the physiological significance of melatonin receptors in ocular tissues. Prog Retin Eye Res. 2008;27:137---160. 4. Alarma-Estrany P, Pintor J. Melatonin receptors in the eye: location, second messengers and role in ocular physiology. Pharmacol Ther. 2007;113:507---522. 5. Crooke A, Guzman-Aranguez A, Mediero A, et al. Effect of melatonin and analogues on corneal wound healing: involvement of Mt(2) melatonin receptor. Curr Eye Res. 2015;40:56---65. 6. Hoyle CHV, Peral A, Pintor J. Melatonin potentiates tear secretion induced by diadenosine tetraphosphate in the rabbit. Eur J Pharmacol. 2006;552:159---161. 7. Karaaslan C, Suzen S. Antioxidant properties of melatonin and its potential action in diseases. Curr Top Med Chem. 2015;15:894---903. 8. Suphakasem S, Lekskul M, Rangsin R. Assessment of different wetting time and paper strip size of Schirmer test in dry eye patients. J Med Assoc Thai. 2012;5:S107---S110. 9. Awad Alkozi H, Pintor J. TRPV4 activation triggers the release of melatonin from human non-pigmented ciliary epithelial cells. Exp Eye Res. 2015;136:34---37. 10. Zawilska J. Daily variation in the concentration of melatonin and 5-methoxytryptophol in the goose pineal gland, retina,and plasma. Gen Comp Endocrinol, 134 (2003), pp. 296-302