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Improving catalase-based propelled motor endurance by enzyme encapsulation†

dc.contributor.authorSimmchen, Juliane
dc.contributor.authorBaeza, Alejandro
dc.contributor.authorRuiz-Molina, Daniel
dc.contributor.authorVallet Regí, María Dulce Nombre
dc.date.accessioned2023-06-19T14:54:39Z
dc.date.available2023-06-19T14:54:39Z
dc.date.issued2014-06-03
dc.description.abstractBiocatalytic propulsion is expected to play an important role in the future of micromotors as it might drastically increase the number of available fuelling reactions. However, most of the enzyme-propelled micromotors so far reported still rely on the degradation of peroxide by catalase, in spite of being vulnerable to relatively high peroxide concentrations. To overcome this limitation, herein we present a strategy to encapsulate the catalase and to graft the resulting enzyme capsules on motor particles. Significant improvement of the stability in the presence of peroxide and other aggressive agents has been observed.
dc.description.departmentDepto. de Química en Ciencias Farmacéuticas
dc.description.facultyFac. de Farmacia
dc.description.refereedTRUE
dc.description.sponsorshipMinisterio de Economía y Competitividad - CICYT
dc.description.sponsorshipComunidad de Madrid
dc.description.statuspub
dc.eprint.idhttps://eprints.ucm.es/id/eprint/30896
dc.identifier.doi10.1039/c4nr02459a
dc.identifier.issn2040-3372, ISSN-L: 2040-3364
dc.identifier.officialurlhttp://dx.doi.org/10.1039/c4nr02459a
dc.identifier.relatedurlhttp://pubs.rsc.org/en/Content/ArticleLanding/2014/NR/C4NR02459A#!divAbstract
dc.identifier.urihttps://hdl.handle.net/20.500.14352/34725
dc.issue.number15
dc.journal.titleNanoscale
dc.language.isoeng
dc.page.final8913
dc.page.initial8907
dc.publisherRoyal Society of Chemistry
dc.relation.projectIDMAT-2008-00736
dc.relation.projectIDMAT2012-38318-C03-02
dc.relation.projectIDMAT2012-35556
dc.relation.projectID(S2009/MAT-172)
dc.rights.accessRightsrestricted access
dc.subject.cdu546
dc.subject.cdu577.15
dc.subject.cdu615.4
dc.subject.keywordEnzimas
dc.subject.keywordCatalasa
dc.subject.keywordTecnología farmacéutica
dc.subject.keywordEnzymes
dc.subject.keywordPharmaceutical technology
dc.subject.keywordMicromotors
dc.subject.keywordOxidation
dc.subject.keywordPeroxides
dc.subject.keywordEnzyme encapsulation
dc.subject.keywordMotor particles
dc.subject.keywordPeroxide concentration
dc.subject.keywordEncapsulation
dc.subject.ucmQuímica inorgánica (Química)
dc.subject.unesco2303 Química Inorgánica
dc.titleImproving catalase-based propelled motor endurance by enzyme encapsulation†
dc.typejournal article
dc.volume.number6
dspace.entity.typePublication
relation.isAuthorOfPublication791023b8-2531-44eb-ba01-56e3b7caa0cb
relation.isAuthorOfPublication.latestForDiscovery791023b8-2531-44eb-ba01-56e3b7caa0cb

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