Psychopathological profiles of adolescent presenting to emergency departments following a suicide attempt: A comprehensive analysis

dc.contributor.authorGarcía Fernández, Ainoa
dc.contributor.authorAyad Ahmed, Wala
dc.contributor.authorDíaz Marsa, Marina Francisca
dc.contributor.authorDe La-Torre Luque, Alejandro Francisco
dc.contributor.authorZorrilla, Iñaki
dc.date.accessioned2025-08-26T07:32:15Z
dc.date.available2025-08-26T07:32:15Z
dc.date.issued2025-07-31
dc.description.abstractBackground. Despite the identification of several risk factors, an understanding of the role of specific psychopathological profiles in association with adolescent suicidal behaviours remains a key challenge in public health research. The study aimed to identify psychopathological profiles in suicidal adolescents and to analyse their association with suicide-related outcomes. Methods. A total of 285 adolescents aged 12 to 17 years [mean age (SD)=14.98 (1.51); females: 249 (87.40%)] who had attempted suicide within the past 10 days were recruited from different Spanish hospitals. Clinical assessments included psychiatric diagnoses, depressive symptoms, trauma, impulsivity, and suicidal thoughts and behaviours. Latent profile analysis was performed to classify subgroups with similar patterns based on self-report Strengths and Difficulties Questionnaire. Logistic regression and generalised linear modelling were applied to examine the relationship between profile membership and suicidal behaviours. Results. Three psychopathological profiles were identified: internalizing symptom profile (52.63%), externalizing symptom profile (24.21%), and low symptom profile (25.58%). The predominantly female internalizing symptom profile members were more likely to report higher levels of psychopathological symptoms, including number of psychiatric diagnoses, depressive symptoms, and trauma (except sexual abuse). Additionally, they had more non-suicidal self-injury and suicidal thoughts and behaviours. Likewise, greater ideation intensity was associated with the internalizing symptom profile compared to other groups, while greater number of previous suicide attempts correlated with an increase in suicidal behaviours. Finally, higher levels of motor impulsivity were associated with a lower probability of suicidal behaviours. Conclusions. Identifying symptom profiles among adolescents who have attempted suicide provides a valuable framework for guiding suicide prevention and personalized interventions. These findings support the use of tailored approaches, such as DBT-A or CBT for internalizing symptoms, and behavioural or family-based interventions for externalizing traits.
dc.description.departmentDepto. de Medicina Legal, Psiquiatría y Patología
dc.description.facultyFac. de Medicina
dc.description.refereedTRUE
dc.description.sponsorshipEuropean Commission
dc.description.sponsorshipMinisterio de Ciencia e Innovación (España)
dc.description.sponsorshipInstituto de Salud Carlos III (España)
dc.description.sponsorshipGobierno del Principado de Asturias
dc.description.sponsorshipFundación La Caixa
dc.description.sponsorshipFundación para la Investigación e Innovación Biosanitaria del Principado de Asturias
dc.description.sponsorshipCentro de Investigación Biomédica en Red de Salud Mental
dc.description.statuspub
dc.identifier.citationGarcía-Fernández, A., Martínez-Cao, C., Pérez-Díez, I., Andreo-Jover, J., Ayad-Ahmed, W., Bobes-Bascarán, T., Canal Rivero, M., Cebriá, A. I., Crespo-Facorro, B., Díaz-Marsa, M., González-Pinto, A., Gómez, S. A., Grande, I., Jiménez-Treviño, L., López, P., Mola-Cardenes, P., Ortiz Villalobos, A., Palao, D. J., Palao-Tarrero, Á., Ruiz Veguilla, M., … Sáiz, P. A. (2025). Psychopathological profiles of adolescent presenting to emergency departments following a suicide attempt: A comprehensive analysis. Journal of psychiatric research, 190, 169–180. Advance online publication. https://doi.org/10.1016/j.jpsychires.2025.07.035
dc.identifier.doi10.1016/j.jpsychires.2025.07.035
dc.identifier.essn1879-1379
dc.identifier.issn0022-3956
dc.identifier.officialurlhttps://doi.org/10.1016/j.jpsychires.2025.07.035
dc.identifier.pmid40774117
dc.identifier.relatedurlhttps://www.sciencedirect.com/science/article/pii/S0022395625004765?via%3Dihub
dc.identifier.relatedurlhttps://pubmed.ncbi.nlm.nih.gov/40774117/
dc.identifier.urihttps://hdl.handle.net/20.500.14352/123369
dc.issue.numberOctober 2025
dc.journal.titleJournal of Psychiatric Research
dc.language.isoeng
dc.page.final180
dc.page.initial169
dc.publisherElsevier
dc.relation.projectIDinfo:eu-repo/grantAgreement/ISCIII/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020 (ISCIII)/PI19%2F00236/ES/PREVENCION E INTERVENCION EN SUICIDIO (SURVIVE): ESTUDIO DE COHORTE Y ENSAYOS CLINICOS CONTROLADOS ANIDADOS DE PROGRAMAS DE PREVENCION SECUNDARIA PARA INTENTOS DE SUICIDIO/
dc.relation.projectIDinfo:eu-repo/grantAgreement/ISCIII/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020 (ISCIII)/PI19%2F00569/ES/PREVENCION E INTERVENCION EN SUICIDIO (SURVIVE): ESTUDIO DE COHORTE Y ENSAYOS CLINICOS CONTROLADOS ANIDADOS DE PROGRAMAS DE PREVENCION SECUNDARIA PARA INTENTOS DE SUICIDIO/
dc.relation.projectIDinfo:eu-repo/grantAgreement/ISCIII/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020 (ISCIII)/PI19%2F00685/ES/PREVENCION E INTERVENCION EN SUICIDIO (SURVIVE): ESTUDIO DE COHORTE Y ENSAYOS CLINICOS CONTROLADOS ANIDADOS DE PROGRAMAS DE PREVENCION SECUNDARIA PARA INTENTOS DE SUICIDIO/
dc.relation.projectIDinfo:eu-repo/grantAgreement/ISCIII/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020 (ISCIII)/PI19%2F00941/ES/PREVENCION E INTERVENCION EN SUICIDIO (SURVIVE): ESTUDIO DE COHORTE Y ENSAYOS CLINICOS CONTROLADOS ANIDADOS DE PROGRAMAS DE PREVENCION SECUNDARIA PARA INTENTOS DE SUICIDIO/
dc.relation.projectIDinfo:eu-repo/grantAgreement/ISCIII/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020 (ISCIII)/PI19%2F00954/ES/PREVENCION E INTERVENCION EN SUICIDIO (SURVIVE): ESTUDIO DE COHORTE Y ENSAYOS CLINICOS CONTROLADOS ANIDADOS DE PROGRAMAS DE PREVENCION SECUNDARIA PARA INTENTOS DE SUICIDIO/
dc.relation.projectIDinfo:eu-repo/grantAgreement/ISCIII/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020 (ISCIII)/PI19%2F01027/ES/PREVENCION E INTERVENCION EN SUICIDIO (SURVIVE): ESTUDIO DE COHORTE Y ENSAYOS CLINICOS CONTROLADOS ANIDADOS DE PROGRAMAS DE PREVENCION SECUNDARIA PARA INTENTOS DE SUICIDIO/
dc.relation.projectIDinfo:eu-repo/grantAgreement/ISCIII/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020 (ISCIII)/PI19%2F01484/ES/PREVENCION E INTERVENCION EN SUICIDIO (SURVIVE): ESTUDIO DE COHORTE Y ENSAYOS CLINICOS CONTROLADOS ANIDADOS DE PROGRAMAS DE PREVENCION SECUNDARIA PARA INTENTOS DE SUICIDIO/
dc.relation.projectIDinfo:eu-repo/grantAgreement/ISCIII/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020 (ISCIII)/PI20%2F00229/ES/PREVENCION E INTERVENCION EN SUICIDIO (SURVIVE): ESTUDIO DE COHORTE Y ENSAYOS CLINICOS CONTROLADOS ANIDADOS DE PROGRAMAS DE PREVENCION SECUNDARIA PARA INTENTOS DE SUICIDIO/
dc.relation.projectIDinfo:eu-repo/grantAgreement/ISCIII /Plan Estatal de Investigación Científica, Técnica y de Innovación para el periodo 2021-2023/PI23%2F01277/ES/SURVIVE 2: Un estudio de cohorte extendida para investigar la conducta suicida en España y la eficacia de estrategias de prevención secundaria. Estudio de Cohorte y Ensayo Clínico Aleatorizado en adolescentes/
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internationalen
dc.rights.accessRightsopen access
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject.cdu616.89
dc.subject.keywordSuicide attempt
dc.subject.keywordAdolescent
dc.subject.keywordPsychopathology symptoms
dc.subject.keywordSymptom profile
dc.subject.keywordLatent profile analysis
dc.subject.ucmPsiquiatría
dc.subject.ucmPsicología clínica y psicodiagnóstico
dc.subject.unesco3211 Psiquiatría
dc.subject.unesco61 Psicología
dc.titlePsychopathological profiles of adolescent presenting to emergency departments following a suicide attempt: A comprehensive analysis
dc.typejournal article
dc.type.hasVersionVoR
dc.volume.number190
dspace.entity.typePublication
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