Analysis of craniocervical abnormalities in osteogenesis imperfecta during growth

Simple item page
dc.contributor.authorNova García, Manuel Joaquín De
dc.contributor.authorGarcía de Sola, Rafael
dc.contributor.authorBurgueño Torres, Laura
dc.date.accessioned2024-03-19T22:18:47Z
dc.date.available2024-03-19T22:18:47Z
dc.date.issued2024-02-18
dc.description.abstractOsteogenesis Imperfecta (OI) is a genetic disease characterized by osteopenia and bone fragility in which the craniocervical junction is also affected. This is of special relevance due to the high prevalence in anomalies described in the literature as follows: basilar invagination, basilar impression, and platybasia. Methods. We analyzed 19 lateral skull radiographs and 14 magnetic resonance images (MRIs) of 28 patients with OI in which eight linear and five angular measurements were plotted to determine the existence of craniocervical junction anomalies and compare them with 38 lateral skull radiographs and 28 MRIs performed on age-matched healthy controls. Results. From the reference values obtained from the control sample for each age group, we established the limit value at which pathology could be suspected. Some of the variables studied showed a clear trend associated with growth. More than half of the patients (60.71%) presented an anomaly in the skull base. Conclusions. According to the diagnostic criteria used and taking +2.5 SD as the limit value, 10.71% of the patients had basilar invagination, 35.71% had basilar impression, and 39.29% had platybasia, the latter being the most common finding
dc.description.departmentDepto. de Especialidades Clínicas Odontológicas
dc.description.facultyFac. de Odontología
dc.description.refereedTRUE
dc.description.statuspub
dc.identifier.citationDe Nova-García MJ, Sola RG, Burgueño-Torres L. Analysis of Craniocervical Abnormalities in Osteogenesis Imperfecta during Growth. Applied Sciences. 2024; 14(4):1640
dc.identifier.doi10.3390/app14041640
dc.identifier.issn2076-3417
dc.identifier.officialurlhttps://www.mdpi.com/2076-3417/14/4/1640
dc.identifier.urihttps://hdl.handle.net/20.500.14352/102394
dc.issue.number4
dc.journal.titleApplied Sciences
dc.language.isoeng
dc.page.initial1640
dc.publisherMDPI
dc.rightsAttribution 4.0 Internationalen
dc.rights.accessRightsopen access
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subject.cdu616.314-053.2
dc.subject.cdu615.849
dc.subject.cdu616.71
dc.subject.cdu572.72
dc.subject.keywordOsteogenesis imperfecta
dc.subject.keywordCraniocervical junction
dc.subject.keywordPlatybasia
dc.subject.keywordBasilar impression
dc.subject.keywordBasilar invagination
dc.subject.keywordMagnetic resonance imaging
dc.subject.ucmCiencias Biomédicas
dc.subject.ucmOdontología (Medicina)
dc.subject.ucmOdontología infantil
dc.subject.ucmDiagnóstico por imagen y medicina nuclear
dc.subject.unesco32 Ciencias Médicas
dc.subject.unesco3207.14 Osteopatología
dc.titleAnalysis of craniocervical abnormalities in osteogenesis imperfecta during growth
dc.typejournal article
dc.type.hasVersionVoR
dc.volume.number14
dspace.entity.typePublication
relation.isAuthorOfPublicationcd7b79cd-2c53-462f-9100-f48e080852a1
relation.isAuthorOfPublication02766f49-7f47-4888-a8d9-1e6c873ee395
relation.isAuthorOfPublication.latestForDiscoverycd7b79cd-2c53-462f-9100-f48e080852a1
Download
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Analysis of Craniocervical Abnormalities in Osteogenesis Imperfecta during Growth.pdf
Size:
1.62 MB
Format:
Adobe Portable Document Format
downoload Download
Collections
Artículos