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Uracil grafted imine-based covalent organic framework for nucleobase recognition

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https://dx.doi.org/10.1039/C8CC04346A

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Publication date

2018

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Royal Society of Chemistry
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https://hdl.handle.net/20.500.14352/129751

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Royuela, Sergio, et al. «Uracil grafted imine-based covalent organic framework for nucleobase recognition». Chemical Communications, vol. 54, no. 63, 2018, pp.8729-8732. https://doi.org/10.1039/C8CC04346A

Abstract

An imine-based covalent organic framework (COF) decorated in its cavities with uracil groups has shown selective recognition towards adenine in water. These results show how the confinement of the base-pair inside the COF's pores allows a remarkable selective recognition in aqueous media.

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This work was financially supported by MINECO (MAT2016-77608-C3-1-P and 2-P, SAF2017-87305-R). IMDEA Nanociencia acknowledges support from the ‘Severo Ochoa’ Programme for Centres of Excellence in R&D (MINECO, Grant SEV-2016-0686). Funding from the European Research Council (ERC-StG 279548) and MINECO (CTQ2014-27729-P and CTQ2017-84727-P) is gratefully acknowledged (DGR).

UCM subjects

Química orgánica (Química), Materiales

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2306 Química Orgánica

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