Atheromatosis of the brain-supplying arteries: Circle of Willis, basilar, vertebral and their branches

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dc.contributor.authorLlopis, Guillermo
dc.contributor.authorQuinones, Sara
dc.contributor.authorKonschake, Marko
dc.contributor.authorSimon De Blas, Clara
dc.contributor.authorHernández, Lorenzo Mauricio
dc.contributor.authorAbramovic, A
dc.contributor.authorViñuela Prieto, José Manuel
dc.contributor.authorSañudo Tejero, José Ramón
dc.contributor.authorTubbs, Richard Shane
dc.contributor.authorMaranillo Alcaide, Eva
dc.date.accessioned2024-01-08T09:38:38Z
dc.date.available2024-01-08T09:38:38Z
dc.date.issued2022-04-01
dc.description.abstractPurpose: Atherosclerotic plaques in the brain-supplying arteries are slowly-developing alterations of vascular structures that can lead to neurological impairment due to stenosis and insufficient oxygenation of eloquent brain areas. The aim of this study is to provide detailed demographic information related to the incidence of atherosclerotic plaques in the cerebral arteries. Material and methods: Forty-eight circles of Willis (21 men, 21 women, mean age: 70.26, six samples unknown) were macroscopically analyzed for length, diameter, and presence of atherosclerotic plaques. Statistical analysis was used to identify potential differences in the locations and frequencies of atherosclerotic plaques in relation to age and sex. Results: The study sample revealed 261 atherosclerotic plaques. The key findings were significant correlations between plaque development and age and between plaque location and age; however, there was no significant sex difference. Conclusion: The upper and lower branches of the middle cerebral artery (MCA) were novel locations predisposing to plaque development. A cut-off value at 60 years revealed a significant difference in plaque development and distribution. There were no significant sex differences in the occurrence of atherosclerotic plaques.
dc.description.departmentDepto. de Anatomía y Embriología
dc.description.facultyFac. de Medicina
dc.description.refereedTRUE
dc.description.statuspub
dc.identifier.citationLlopis G, Quinones S, Konschake M, Simon De Blas C, Hernández LM, Abramovic A, Viñuela-Prieto JM, Sanudo J, Tubbs RS, Maranillo E. Atheromatosis of the brain-supplying arteries: Circle of Willis, basilar, vertebral and their branches. Ann Anat. 2022 Aug;243:151941. doi: 10.1016/j.aanat.2022.151941. Epub 2022 Apr 1. PMID: 35378255.
dc.identifier.doi10.1016/j.aanat.2022.151941
dc.identifier.essn1618-0402
dc.identifier.issn0940-9602
dc.identifier.officialurlhttp://www.sciencedirect.com/science/journal/09409602
dc.identifier.relatedurlwww.elsevier.com/locate/aanat
dc.identifier.relatedurlhttps://www-sciencedirect-com.bucm.idm.oclc.org/science/article/pii/S0940960222000565?via%3Dihub
dc.identifier.urihttps://hdl.handle.net/20.500.14352/91779
dc.issue.number151941
dc.journal.titleAnnals of Anatomy
dc.language.isoeng
dc.page.final9
dc.page.initial1
dc.publisherElsevier
dc.rightsAttribution 4.0 Internationalen
dc.rights.accessRightsopen access
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subject.cdu616.8
dc.subject.keywordAtherosclerosis
dc.subject.keywordBrain arteries
dc.subject.keywordCircle of Willis
dc.subject.ucmCiencias Biomédicas
dc.subject.unesco2410.02 Anatomía Humana
dc.subject.unesco3213.17 Cirugía Vascular
dc.subject.unesco3213.08 Neurocirugía
dc.titleAtheromatosis of the brain-supplying arteries: Circle of Willis, basilar, vertebral and their branches
dc.typejournal article
dc.type.hasVersionVoR
dc.volume.number243
dspace.entity.typePublication
relation.isAuthorOfPublicationdcb63eb9-b997-4f0a-a8f3-5f8b72d9ea08
relation.isAuthorOfPublicationc205208c-cdd9-4b73-ab05-35ee28af173f
relation.isAuthorOfPublication.latestForDiscoverydcb63eb9-b997-4f0a-a8f3-5f8b72d9ea08
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