Influence of platelet-rich plasma on the histologic charcteristics of the autologous fat graft to the upper lip of rabbits

dc.contributor.authorRodríguez-Flores, Jordi
dc.contributor.authorPalomar Gallego, María Angustias
dc.contributor.authorEnguita Valls, Ana Belén
dc.contributor.authorRodríguez Peralto, José Luis
dc.contributor.authorTorres García-Denche, Jesús
dc.date.accessioned2023-06-20T03:50:31Z
dc.date.available2023-06-20T03:50:31Z
dc.date.issued2011
dc.description.abstractBackground: This study evaluated the influence of platelet-rich plasma (PRP) on the histologic characteristics of autologous fat grafts to the upper lip of rabbits. Methods: Nine New Zealand white rabbits were used. eight of the rabbits underwent fat harvest from the groin fat pads using a modified Coleman technique. One side of the upper lip was infiltrated with autologous fat and the other side with fat and PRP. Four of the inflitrated rabbits were killed 8 weeks after the lip augmentation, and the remaining four infiltrated rabbits plus one control case were killed 12 weeeks after the procedure. Coronal sections of both upper lips were analyzed microscopically to evaluate the quality of the fat graft, the inflammtory reaction, the presence of oil cysts, the degree of fibrosis, and the neovascularization. Results: The infiltration of adipose tissue plus PRP presented less inflammtory reaction (p<0.05) and fewer oil cysts (p<0.05) than the infiltration of isolated fat. Platelet-rich plasma increases the maintenance of the transplanted fat cells.
dc.description.departmentDepto. de Odontología Conservadora y Prótesis
dc.description.facultyFac. de Odontología
dc.description.refereedTRUE
dc.description.statuspub
dc.eprint.idhttps://eprints.ucm.es/id/eprint/29949
dc.identifier.doidoi 10.1007/s00266-010-9640-5
dc.identifier.issn0364-216X
dc.identifier.urihttps://hdl.handle.net/20.500.14352/44538
dc.journal.titleAesthetic Plastic Surgery
dc.language.isospa
dc.page.final486
dc.page.initial480
dc.publisherSpringer
dc.rights.accessRightsopen access
dc.subject.cdu616.31-089
dc.subject.keywordFat graft
dc.subject.keywordPlatelet-rich plasma
dc.subject.ucmCirugía bucofacial
dc.titleInfluence of platelet-rich plasma on the histologic charcteristics of the autologous fat graft to the upper lip of rabbits
dc.typejournal article
dc.volume.number35
dspace.entity.typePublication
relation.isAuthorOfPublicationc3c63d70-a9a2-4a70-8f59-313474b01041
relation.isAuthorOfPublication9a1b056b-ced8-48af-87ca-f5c7131d46e7
relation.isAuthorOfPublication.latestForDiscoveryc3c63d70-a9a2-4a70-8f59-313474b01041
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