Tuning mesoporous silica dissolution in physiological environments: a review

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dc.contributor.authorParis, J.L.
dc.contributor.authorColilla Nieto, Montserrat
dc.contributor.authorIzquierdo Barba, Isabel
dc.contributor.authorManzano García, Miguel
dc.contributor.authorVallet Regí, María Dulce Nombre
dc.date.accessioned2023-06-17T21:51:31Z
dc.date.available2023-06-17T21:51:31Z
dc.date.issued2017
dc.descriptionRESEARCHER ID K-3719-2014 (Miguel Manzano García) ORCID 0000-0001-6238-6111 (Miguel Manzano García) RESEARCHER ID M-3378-2014 (María Vallet Regí) ORCID 0000-0002-6104-4889 (María Vallet Regí)
dc.description.abstractMatrix degradation has a major impact on the release kinetics of drug delivery systems. Regarding ordered mesoporous silica materials for biomedical applications, their dissolution is an important parameter that should be taken into consideration. In this paper, we review the main factors that govern the mesoporous silica dissolution in physiological environments. We also provide the necessary knowledge to researchers in the area for tuning the dissolution rate of those matrices, so the degradation could be controlled and the material behaviour optimised.
dc.description.departmentDepto. de Química en Ciencias Farmacéuticas
dc.description.facultyFac. de Farmacia
dc.description.refereedTRUE
dc.description.sponsorshipUnión Europea. H2020
dc.description.sponsorshipMinisterio de Economía y Competitividad (MINECO)
dc.description.sponsorshipSecretaría de Estado de Investigación, Desarrollo e Innovación
dc.description.statusinpress
dc.eprint.idhttps://eprints.ucm.es/id/eprint/41657
dc.identifier.doiDOI 10.1007/s10853-017-0787-1
dc.identifier.issn0022-2461
dc.identifier.officialurlhttps://link.springer.com/
dc.identifier.urihttps://hdl.handle.net/20.500.14352/17663
dc.journal.titleJournal of Materials Science
dc.language.isospa
dc.publisherSpringer Verlag
dc.relation.projectIDMOZART (685872)
dc.relation.projectIDVERDI (694160)
dc.relation.projectIDCSO2010-11384-E
dc.relation.projectIDMAT2015-64831-R
dc.relation.projectIDBES-2013-064182
dc.rights.accessRightsopen access
dc.subject.cdu546
dc.subject.cdu66
dc.subject.cdu615.46
dc.subject.keywordSilica dissolution
dc.subject.keywordmatrix degradation
dc.subject.keyworddrug delivery systems
dc.subject.keywordmesoporous silica nanoparticles
dc.subject.ucmQuímica inorgánica (Farmacia)
dc.titleTuning mesoporous silica dissolution in physiological environments: a review
dc.typejournal article
dspace.entity.typePublication
relation.isAuthorOfPublication449a114d-e3bf-4d4c-81c5-2b0c5f050b9d
relation.isAuthorOfPublicationee9272a2-db11-4efb-97f8-7ce1a18ad55e
relation.isAuthorOfPublication2a7febe9-6dd2-4117-aa12-552e54c12bd3
relation.isAuthorOfPublication791023b8-2531-44eb-ba01-56e3b7caa0cb
relation.isAuthorOfPublication.latestForDiscovery2a7febe9-6dd2-4117-aa12-552e54c12bd3
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