Publication:
Changes in Intestinal Microbiota and Predicted Metabolic Pathways During Colonic Fermentation of Mango (Mangifera indica L.)—Based Bar Indigestible Fraction

dc.contributor.authorGutiérrez Sarmiento, Wilbert
dc.contributor.authorSáyago Ayerdi, Sonia Guadalupe
dc.contributor.authorGoñi Cambrodón, Isabel
dc.contributor.authorGutiérrez Miceli, Federico Antonio
dc.contributor.authorAbud-Archila, Miguel
dc.contributor.authorRejón Orantes, José del Carmen
dc.contributor.authorRincón Rosales, Reiner
dc.contributor.authorPeña Ocaña, Betsy Anaid
dc.contributor.authorRuíz Valdiviezo, Víctor Manuel
dc.date.accessioned2023-06-17T09:21:30Z
dc.date.available2023-06-17T09:21:30Z
dc.date.issued2020-03-03
dc.description.abstractMango (Mangifera indica L.) peel and pulp are a source of dietary fiber (DF) and phenolic compounds (PCs) that constituent part of the indigestible fraction (IF). This fraction reaches the colon and acts as a carbon and energy source for intestinal microbiota. The effect of mango IF on intestinal microbiota during colonic fermentation is unknown. In this study, the isolated IF of a novel ‘Ataulfo’ mango-based bar (snack) UV-C irradiated and non irradiated (UVMangoBand MangoB) were fermented. Colonic fermentation occurred in vitro under chemical-enzymatic, semi-anaerobic, batch culture and controlled pH colonic conditions. Changes in the structure of fecal microbiota were analyzed by 16s rRNA gene Illumina MiSeq sequencing. The community´s functional capabilities were determined in silico. The MangoB and UVMangoB increased the presence of Faecalibacterium, Roseburia, Eubacterium, Fusicatenibacter, Holdemanella, Catenibacterium, Phascolarctobacterium, Buttiauxella, Bifidobacterium, Collinsella, Prevotella and Bacteroides genera. The alpha indexes showed a decrease in microbial diversity after 6 h of colonic fermentation. The coordinates analysis indicated any differences between irradiated and non-irradiated bar. The metabolic prediction demonstrated that MangoB and UVMangoB increase the microbiota carbohydrate metabolism pathway. This study suggests that IF of mango-based bar induced beneficial changes on microbial ecology and metabolic pathway that could be promissory to prevention or treatment of metabolic dysbiosis. However, in vivo interventions are necessary to confirm the interactions between microbiota modulating and intestinal beneficial effects.
dc.description.departmentDepto. de Nutrición y Ciencia de los Alimentos
dc.description.facultyFac. de Farmacia
dc.description.refereedTRUE
dc.description.sponsorshipConsejo Nacional de Ciencia y Tecnología (CONACYT), Mexico
dc.description.sponsorshipTecnológico Nacional de México (TECNM)
dc.description.statuspub
dc.eprint.idhttps://eprints.ucm.es/id/eprint/69665
dc.identifier.doi10.3390/nu12030683
dc.identifier.issn2072-6643
dc.identifier.officialurlhttps://doi.org/10.3390/nu12030683
dc.identifier.relatedurlhttps://www.mdpi.com/2072-6643/12/3/683
dc.identifier.urihttps://hdl.handle.net/20.500.14352/8651
dc.issue.number3
dc.journal.titleNutrients
dc.language.isoeng
dc.page.initial683
dc.publisherMDPI
dc.relation.projectID636047
dc.relation.projectID6257.19-P.
dc.rightsAtribución 3.0 España
dc.rights.accessRightsopen access
dc.rights.urihttps://creativecommons.org/licenses/by/3.0/es/
dc.subject.cdu612.39
dc.subject.keyword: “Ataulfo” mango
dc.subject.keywordin vitro colonic fermentation
dc.subject.keywordintestinal microbiota
dc.subject.keyword16S rRNA gene
dc.subject.keywordbioinformatics
dc.subject.ucmDietética y nutrición (Farmacia)
dc.titleChanges in Intestinal Microbiota and Predicted Metabolic Pathways During Colonic Fermentation of Mango (Mangifera indica L.)—Based Bar Indigestible Fraction
dc.typejournal article
dc.volume.number12
dspace.entity.typePublication
relation.isAuthorOfPublication91fbbf44-879b-4e53-a8c4-dba1778f940b
relation.isAuthorOfPublication.latestForDiscovery91fbbf44-879b-4e53-a8c4-dba1778f940b
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