Hepatosplenic and renal embolisms in infective endocarditis

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dc.contributor.authorLuaces Méndez, María
dc.contributor.authorVilacosta, Isidre
dc.contributor.authorSarriá, Cristina
dc.contributor.authorFernández Pérez, Cristina
dc.contributor.authorSan Román, José
dc.contributor.authorSanmartín, Juan
dc.contributor.authorLópez, Javier
dc.contributor.authorRodríguez, Enrique
dc.date.accessioned2024-02-12T09:35:55Z
dc.date.available2024-02-12T09:35:55Z
dc.date.issued2004
dc.description.abstractIntroduction and objectives: Among the complications of infective endocarditis, systemic embolisms are an ominous prognostic sign. The aim of the present study was to compare the demographic, clinical, microbiologic and echocardiographic features of episodes of endocarditis accompanied and unaccompanied by embolisms in the spleen, kidney or liver. We also assessed the prognostic impact of these embolisms. Material and method: Prospective, multicenter clinical cohort study. We analyzed 338 consecutive episodes of left-sided infective endocarditis in 308 patients. Episodes were classified in two groups: group I, episodes with hepatosplenic or renal embolisms (n=34); group II, episodes without embolisms (n=304). Results: There were 41 embolisms in 34 episodes (10%). Of these, 34 were located in the spleen, 5 in the kidney and 2 in the liver. Some forms of clinical presentation predominated in group I, e.g., abdominal pain, splenomegaly, cutaneous stigmata, hematuria, embolisms in other locations, and septic shock. Staphylococcus aureus and enterococci were more commonly isolated in group I. Detection of vegetations (by transesophageal echocardiography) was more frequent in group I, and they were larger than vegetations in group II. Hepatosplenic and renal embolisms were not independently associated with the need for cardiac surgery or death. Conclusions: Hepatosplenic and renal embolisms occur in 10% of left-sided episodes of infective endocarditis. The clinical presentation of these episodes has characteristic features. Vegetations are larger than in episodes without these embolism. Hepatosplenic and renal embolisms do not increase neither the need of cardiac surgery nor the risk of death.
dc.description.departmentDepto. de Fisiología
dc.description.facultyFac. de Medicina
dc.description.refereedTRUE
dc.description.statuspub
dc.identifier.citationLuaces Méndez M, Vilacosta I, Sarriá C, Fernández C, San Román JA, Sanmartín JV, López J, Rodríguez E. Endocarditis infecciosa y embolias del eje hepatoesplenorrenal [Hepatosplenic and renal embolisms in infective endocarditis]. Rev Esp Cardiol. 2004 Dec;57(12):1188-96. Spanish. PMID: 15617642.
dc.identifier.doi10.1157/13069865
dc.identifier.officialurlhttps://www.doi.org/10.1157/13069865
dc.identifier.relatedurlhttps://pubmed.ncbi.nlm.nih.gov/15617642/
dc.identifier.urihttps://hdl.handle.net/20.500.14352/101164
dc.issue.number12
dc.journal.titleRevista Espanola de Cardiologia
dc.language.isospa
dc.page.final1196
dc.page.initial1188
dc.publisherElsevier
dc.rights.accessRightsrestricted access
dc.subject.cdu616.126-002
dc.subject.ucmCiencias Biomédicas
dc.subject.unesco32 Ciencias Médicas
dc.titleHepatosplenic and renal embolisms in infective endocarditis
dc.title.alternativeEndocarditis infecciosa y embolias del eje hepatoesplenorrenal
dc.typejournal article
dc.type.hasVersionVoR
dc.volume.number57
dspace.entity.typePublication
relation.isAuthorOfPublicationcacd1d83-3ad8-4829-8684-d90aa041927b
relation.isAuthorOfPublicatione3b551e4-0127-4a0e-ad9e-2232be67b78b
relation.isAuthorOfPublication.latestForDiscoverycacd1d83-3ad8-4829-8684-d90aa041927b
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