Influence of Contact Lens Parameters on Tear Film Dynamics

dc.contributor.authorRamasubramanian, Darshan
dc.contributor.authorHernández Verdejo, José Luis
dc.contributor.authorLópez Alonso, José Manuel
dc.date.accessioned2025-02-26T15:23:24Z
dc.date.available2025-02-26T15:23:24Z
dc.date.issued2025-02
dc.descriptionEsta publicación estará en acceso abierto a partir del 19 de febrero de 2026, tal y como marcan las políticas editoriales.
dc.description.abstractThis study employs a computational model to simulate the dynamics of tear fluid and tear film in conjunction with contact lens motion, examining the interplay between diverse contact lens characteristics—such as material, design, and dimensions—and key ocular factors like dry eye conditions, corneal size, and blink rate. These interactions are critical for customising lens fit to maximise wearer comfort. Utilising optical measurements from a single participant, the study integrates data on tear meniscus size, blink velocity, and palpebral fissure height with sixteen different contact lens parameters, including Young's modulus, thickness, diameter, and curvature. Correlation analyses were conducted to determine the impact of these parameters on the dynamics of the tear fluid and overall tear film. Results show that the diameter and Young's modulus of the contact lens significantly influence pre-lens tear film thickness, with robust, statistically significant correlations. In contrast, lens thickness and base curve showed minimal impact, as evidenced by weak and non-significant correlations. These findings underscore the critical roles of lens diameter and Young's modulus in enhancing the stability and distribution of tear fluid, thereby improving wearer comfort and advancing contact lens design.
dc.description.departmentDepto. de Optometría y Visión
dc.description.facultyFac. de Óptica y Optometría
dc.description.refereedTRUE
dc.description.sponsorshipEuropean Commission
dc.description.statuspub
dc.identifier.citationRamasubramanian, D., Hernández-Verdejo, J.L. & López-Alonso, J.M. Influence of Contact Lens Parameters on Tear Film Dynamics. Bull Math Biol 87, 45 (2025). https://doi.org/10.1007/s11538-025-01425-1
dc.identifier.doi10.1093/imammb/dqab010
dc.identifier.officialurlhttps://doi.org/10.1093/imammb/dqab010
dc.identifier.urihttps://hdl.handle.net/20.500.14352/118339
dc.journal.titleBulletin of Mathematical Biology
dc.language.isoeng
dc.publisherSpringer
dc.relation.projectIDinfo:eu-repo/grantAgreement/EC/H2020/956274
dc.rights.accessRightsembargoed access
dc.subject.cdu617.7-089.243
dc.subject.keywordContact lens design
dc.subject.keywordTear fluid
dc.subject.keywordTear film dynamics
dc.subject.keywordCorrelation analysis
dc.subject.keywordWearer comfort
dc.subject.ucmÓptica y optometría
dc.subject.unesco32 Ciencias Médicas
dc.subject.unesco2209.15 Optometría
dc.titleInfluence of Contact Lens Parameters on Tear Film Dynamics
dc.typejournal article
dc.type.hasVersionVoR
dc.volume.number87
dspace.entity.typePublication
relation.isAuthorOfPublication2ed110d3-f335-4688-9c14-1a56e56e8d28
relation.isAuthorOfPublicatione52aef01-c246-4f9f-9cfd-d9dfb2a8ee79
relation.isAuthorOfPublication.latestForDiscovery2ed110d3-f335-4688-9c14-1a56e56e8d28

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