Coexistence of mcr-1 and blaNDM-1 in Escherichia coli from Venezuela
| dc.contributor.author | Delgado Blas, José Francisco | |
| dc.contributor.author | Martínez Ovejero, Cristina | |
| dc.contributor.author | Abadia Patiño, Lorena | |
| dc.contributor.author | González Zorn, Bruno | |
| dc.date.accessioned | 2023-06-17T23:53:49Z | |
| dc.date.available | 2023-06-17T23:53:49Z | |
| dc.date.issued | 2016-10 | |
| dc.description.abstract | We studied the presence of the mobile colistin resistance gene mcr-1 in human, animal, and environmental Enterobacteriaceae samples from Cumana, Venezuela, that were collected in 2015. The mcr-1 gene was detected in 2/93 Escherichia coli isolates from swine (novel ST452) and human (ST19) samples that were resistant to colistin. Whole-genome sequencing and transformation experiments identified mcr-1 on an IncI2 plasmid. One of the isolates also bore the widely spread carbapenemase NDM-1. A One Health approach is necessary to further elucidate the flux of these high-risk genes. | |
| dc.description.faculty | Centro de Vigilancia Sanitaria Veterinaria (VISAVET) | |
| dc.description.refereed | TRUE | |
| dc.description.sponsorship | Unión Europea. FP7 | |
| dc.description.sponsorship | Ministerio de Economía y Competitividad (MINECO) | |
| dc.description.status | pub | |
| dc.eprint.id | https://eprints.ucm.es/id/eprint/39608 | |
| dc.identifier.doi | 10.1128/AAC.01319-16 | |
| dc.identifier.issn | 0066-4804 | |
| dc.identifier.officialurl | http://aac.asm.org/content/60/10/6356.long | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14352/18986 | |
| dc.issue.number | 10 | |
| dc.journal.title | Antimicrobial agents and chemotherapy | |
| dc.language.iso | eng | |
| dc.page.final | 8 | |
| dc.page.initial | 6356 | |
| dc.publisher | American Society for Microbiology | |
| dc.relation.projectID | EFFORT (613754) | |
| dc.relation.projectID | EVOTAR (282004) | |
| dc.relation.projectID | BES-2015-073164 | |
| dc.rights.accessRights | restricted access | |
| dc.subject.ucm | Veterinaria | |
| dc.subject.unesco | 3109 Ciencias Veterinarias | |
| dc.title | Coexistence of mcr-1 and blaNDM-1 in Escherichia coli from Venezuela | |
| dc.type | journal article | |
| dc.volume.number | 60 | |
| dspace.entity.type | Publication | |
| relation.isAuthorOfPublication | cc3429de-f0f5-4e10-a62f-7e323338210f | |
| relation.isAuthorOfPublication | abbfe61a-3e58-4cfb-85fc-d2e2ec46b0a3 | |
| relation.isAuthorOfPublication.latestForDiscovery | cc3429de-f0f5-4e10-a62f-7e323338210f |
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