Genotypic versus Phenotypic Characterization, with Respect to β-Lactam Susceptibility, of Haemophilus influenzae Isolates Exhibiting Decreased Susceptibility to β-Lactam Resistance Markers
Loading...
Official URL
Full text at PDC
Publication date
2009
Advisors (or tutors)
Editors
Journal Title
Journal ISSN
Volume Title
Publisher
American Society for Microbiology
Citations
Exportar
Citation
Sevillano D, Giménez MJ, Cercenado E, Cafini F, Gené A, Alou L, Marco F, Martínez-Martínez L, Coronel P, Aguilar L. Genotypic versus phenotypic characterization, with respect to beta-lactam susceptibility, of Haemophilus influenzae isolates exhibiting decreased susceptibility to beta-lactam resistance markers. Antimicrob Agents Chemother. 2009 Jan;53(1):267-70.
Abstract
Among 165 Spanish Haemophilus influenzae isolates with mutations in the ftsI gene (ftsI+) (2005 to 2007), 73% were β-lactamase negative and 26.7% were positive. The proportion of β-lactamase-negative isolates to β-lactamase-positive isolates was 2:1 to 4:1 in general, versus 1:3 in pediatric hospitals. Among 44 β-lactamase-positive strains, 8 strains produced ROB-1 (5 from the pediatric hospital). β-Lactamase-positive ftsI+ strains were phylogenetically closer than were β-lactamase-negative strains.