Desarrollo de herramientas de procesado de imágenes e inteligencia artificial para la valoración de las glándulas de Meibomio
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2024
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19/04/2024
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Universidad Complutense de Madrid
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Abstract
Las glándulas de Meibomio son glándulas sebáceas ubicadas en los tarsos palpebrales encargadas de secretar lípidos a la película lagrimal, estos lípidos reciben el nombre de meibum. El meibum es liberado directamente a la película lagrimal a través de los orificios del borde libre del párpado, siendo éste un componente fundamental de la capa lipídica lagrimal, aportando estabilidad, evitando su evaporación y haciendo de barrera contra agentes externos. Para el estudio de las glándulas de Meibomio es necesaria la realización de un conjunto de pruebas de sintomatología y test clínicos, ya que, no existe una prueba Gold Standard determinada para el diagnóstico de patologías relacionadas con las mismas. Una de las pruebas más características para su valoración y visualización es la llamada meibografía, técnica especializada de imagen que ha ido evolucionando a lo largo de más de 40 años de historia. Actualmente, esta técnica utiliza, en la mayoría de instrumentos desarrollados, luz Infrarroja para observar las estructuras glandulares...
Meibomian glands are sebaceous glands located in both eyelids, these glands are responsible for secreting lipids to the tear film, these lipids are called meibum. Meibum is released directly to the tear film through the holes in the free edge of the eyelid, being a fundamental component of the tear film lipid layer, providing stability, preventing its evaporation and acting as a barrier against external agents.It is necessary to perform a set of symptomatology and clinical tests to study the Meibomian gland, because there is no specific Gold Standard test for the diagnosis of pathologies related this glands. One of the most characteristic tests for the assessment and visualization of Meibomian glands is meibography. Meibograpphy is a specialized imaging technique that has been developed over more than 40 years of history. Currently, these technique use infrared light to observe glandular structures...
Meibomian glands are sebaceous glands located in both eyelids, these glands are responsible for secreting lipids to the tear film, these lipids are called meibum. Meibum is released directly to the tear film through the holes in the free edge of the eyelid, being a fundamental component of the tear film lipid layer, providing stability, preventing its evaporation and acting as a barrier against external agents.It is necessary to perform a set of symptomatology and clinical tests to study the Meibomian gland, because there is no specific Gold Standard test for the diagnosis of pathologies related this glands. One of the most characteristic tests for the assessment and visualization of Meibomian glands is meibography. Meibograpphy is a specialized imaging technique that has been developed over more than 40 years of history. Currently, these technique use infrared light to observe glandular structures...
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Tesis inédita de la Universidad Complutense de Madrid, Facultad de Óptica y Optometría, leída el 19-04-2024