Aviso: para depositar documentos, por favor, inicia sesión e identifícate con tu cuenta de correo institucional de la UCM con el botón MI CUENTA UCM. No emplees la opción AUTENTICACIÓN CON CONTRASEÑA
 

Differential Effect of Modified Medical Research Council Dyspnea, COPD Assessment Test, and Clinical COPD Questionnaire for Symptoms Evaluation Within the New GOLD Staging and Mortality in COPD

dc.contributor.authorCasanova, Ciro
dc.contributor.authorLucas Ramos, Pilar De
dc.contributor.authorCalle Rubio, Myrian
dc.contributor.authorde Torres, Juan
dc.date.accessioned2024-01-31T08:28:50Z
dc.date.available2024-01-31T08:28:50Z
dc.date.issued2015
dc.description.abstractObjective: The modified Medical Research Council (mMRC) dyspnea, the COPD Assessment Test (CAT), and the Clinical COPD Questionnaire (CCQ) have been interchangeably proposed by GOLD (Global Initiative for Chronic Obstructive Lung Disease) for assessing symptoms in patients with COPD. However, there are no data on the prognostic value of these tools in terms of mortality. We endeavored to evaluate the prognostic value of the CAT and CCQ scores and compare them with mMRC dyspnea. Methods: We analyzed the ability of these tests to predict mortality in an observational cohort of 768 patients with COPD (82% men; FEV1, 60%) from the COPD History Assessment in Spain (CHAIN) study, a multicenter observational Spanish cohort, who were monitored annually for a mean follow-up time of 38 months. Results: Subjects who died (n = 73; 9.5%) had higher CAT (14 vs 11, P = .022), CCQ (1.6 vs 1.3, P = .033), and mMRC dyspnea scores (2 vs 1, P < .001) than survivors. Receiver operating characteristic analysis showed that higher CAT, CCQ, and mMRC dyspnea scores were associated with higher mortality (area under the curve: 0.589, 0.588, and 0.649, respectively). CAT scores ≥ 17 and CCQ scores > 2.5 provided a similar sensitivity than mMRC dyspnea scores ≥ 2 to predict all-cause mortality. Conclusions: The CAT and the CCQ have similar ability for predicting all-cause mortality in patients with COPD, but were inferior to mMRC dyspnea scores. We suggest new thresholds for CAT and CCQ scores based on mortality risk that could be useful for the new GOLD grading classification.
dc.description.departmentDepto. de Medicina
dc.description.facultyFac. de Medicina
dc.description.refereedTRUE
dc.description.statuspub
dc.identifier.citationCasanova C, Marín JM, Martínez-González C, de Lucas-Ramos P, Mir-Viladrich I, Cosio B, Peces-Barba G, Solanes-García I, Agüero R, Feu-Collado N, Calle-Rubio M, Alfageme I, de Diego-Damia A, Irigaray R, Marín M, Balcells E, Llunell A, Galdiz JB, Golpe R, Lacarcel C, Cabrera C, Marin A, Soriano JB, Lopez-Campos JL, Soler-Cataluña JJ, de-Torres JP; COPD History Assessment in Spain (CHAIN) Cohort. Differential Effect of Modified Medical Research Council Dyspnea, COPD Assessment Test, and Clinical COPD Questionnaire for Symptoms Evaluation Within the New GOLD Staging and Mortality in COPD. Chest. 2015;148:159-68.
dc.identifier.doi10.1378/chest.14-2449
dc.identifier.issn0012-3692
dc.identifier.officialurlhttps://doi.org/10.1378/chest.14-2449
dc.identifier.relatedurlhttps://pubmed.ncbi.nlm.nih.gov/25612228/
dc.identifier.urihttps://hdl.handle.net/20.500.14352/96861
dc.issue.number1
dc.journal.titleChest
dc.language.isoeng
dc.page.final168
dc.page.initial159
dc.publisherElsevier
dc.rights.accessRightsrestricted access
dc.subject.cdu616.24
dc.subject.ucmNeumología
dc.subject.unesco3205.08 Enfermedades Pulmonares
dc.titleDifferential Effect of Modified Medical Research Council Dyspnea, COPD Assessment Test, and Clinical COPD Questionnaire for Symptoms Evaluation Within the New GOLD Staging and Mortality in COPD
dc.typejournal article
dc.type.hasVersionVoR
dc.volume.number148
dspace.entity.typePublication
relation.isAuthorOfPublication889bc2b1-f6b6-46c3-83d5-a64bdf671c0e
relation.isAuthorOfPublicationa4ef01b8-3d18-4301-bc3a-b259e0d87e1e
relation.isAuthorOfPublication.latestForDiscoverya4ef01b8-3d18-4301-bc3a-b259e0d87e1e

Download

Original bundle

Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
New_GOLD_Staging_and_Mortality_in_COPD.pdf
Size:
854.66 KB
Format:
Adobe Portable Document Format

Collections