Comparing Markov and non-Markov alternatives for cost-effectiveness analysis: insights from a cervical cancer case

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dc.contributor.authorDel Campo Campos, Cristina
dc.contributor.authorBai, Jiaru
dc.contributor.authorKeller, L. Robin
dc.date.accessioned2024-04-25T08:51:58Z
dc.date.available2024-04-25T08:51:58Z
dc.date.issued2019-06
dc.description.abstractMarkov model allows medical prognosis to be modeled with health state transitions over time and are particularly useful for decisions regarding diseases where uncertain events and outcomes may occur. To provide sufficient detail for operations researchers to carry out a Markov analysis, we present a detailed example of a Markov model with five health states with monthly transitions with stationary transition probabilities between states to model the cost and effectiveness of two treatments for advanced cervical cancer. A different approach uses survival curves to directly model the fraction of patients in each state at each time period without the Markov property. We use this alternative method to analyze the cervical cancer case and compare the Markov and non-Markov approaches. These models provide useful insights about both the effectiveness of treatments and the associated costs for healthcare decision makers.
dc.description.departmentDepto. de Economía Financiera y Actuarial y Estadística
dc.description.facultyFac. de Ciencias Económicas y Empresariales
dc.description.refereedTRUE
dc.description.statuspub
dc.identifier.citationdel Campo, C., Bai, J., & Keller, L. R. (2019). Comparing Markov and non-Markov alternatives for cost-effectiveness analysis: Insights from a cervical cancer case. Operations Research for Health Care, 21, 32-43.
dc.identifier.doi10.1016/j.orhc.2019.04.001
dc.identifier.essn2211-6931
dc.identifier.issn2211-6923
dc.identifier.officialurlhttps://doi.org/10.1016/j.orhc.2019.04.001
dc.identifier.urihttps://hdl.handle.net/20.500.14352/103478
dc.journal.titleOperations Research for Health Care
dc.language.isoeng
dc.page.final43
dc.page.initial32
dc.publisherElsevier
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internationalen
dc.rights.accessRightsopen access
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject.keywordCost-effectiveness analysis
dc.subject.keywordMarkov process
dc.subject.keywordSurvival analysis
dc.subject.keywordStationary probabilities
dc.subject.keywordTime-dependent probabilities
dc.subject.ucmProcesos estocásticos
dc.subject.ucmEconomía
dc.subject.ucmInvestigación operativa (Estadística)
dc.subject.ucmOncología
dc.subject.unesco1208.06 Procesos de Markov
dc.subject.unesco1207 Investigación Operativa
dc.subject.unesco3201.01 Oncología
dc.titleComparing Markov and non-Markov alternatives for cost-effectiveness analysis: insights from a cervical cancer case
dc.typejournal article
dc.type.hasVersionAM
dc.volume.number21
dspace.entity.typePublication
relation.isAuthorOfPublication6c714f02-4316-4960-ac6a-4cbbf3e7f233
relation.isAuthorOfPublication.latestForDiscovery6c714f02-4316-4960-ac6a-4cbbf3e7f233
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