Towards the development of smart 3D “gated scaffolds” for on-command delivery
dc.contributor.author | Mas, Núria | |
dc.contributor.author | Arcos Navarrete, Daniel | |
dc.contributor.author | Polo, Lorena | |
dc.contributor.author | Aznar, Elena | |
dc.contributor.author | Sánchez Salcedo, Sandra | |
dc.contributor.author | Sancenón, Félix | |
dc.contributor.author | García Fontecha, Ana | |
dc.contributor.author | Marcos Vega, M. Dolores | |
dc.contributor.author | Baeza, Alejandro | |
dc.contributor.author | Vallet Regí, María Dulce Nombre | |
dc.contributor.author | Martínez-Máñez, Ramón | |
dc.date.accessioned | 2023-06-19T14:54:42Z | |
dc.date.available | 2023-06-19T14:54:42Z | |
dc.date.issued | 2014 | |
dc.description.abstract | A new approach towards the design of “gated scaffolds” based on the combination of capped mesoporous silica nanoparticles (MSNs) with porous biomaterials is reported. Using this approach, a 3D gelatin-based scaffold able to selectively deliver cargo in the presence of an APase enzyme is prepared and tested. This new design opens up the possibility of developing new smart biomaterials with advanced drug-delivery features. | |
dc.description.department | Depto. de Química en Ciencias Farmacéuticas | |
dc.description.faculty | Fac. de Farmacia | |
dc.description.refereed | TRUE | |
dc.description.sponsorship | Spanish Government | |
dc.description.sponsorship | Generalitat Valenciana | |
dc.description.sponsorship | CIBER-BBN | |
dc.description.status | pub | |
dc.eprint.id | https://eprints.ucm.es/id/eprint/30905 | |
dc.identifier.doi | 10.1002/smll.201401227 | |
dc.identifier.issn | 1613-6829 | |
dc.identifier.officialurl | http://dx.doi.org/10.1002/smll.201401227 | |
dc.identifier.uri | https://hdl.handle.net/20.500.14352/34729 | |
dc.issue.number | 23 | |
dc.journal.title | Small | |
dc.language.iso | eng | |
dc.page.final | 4864 | |
dc.page.initial | 4859 | |
dc.publisher | Wiley-VCH | |
dc.relation.projectID | MAT2012-38429-C04-01 | |
dc.relation.projectID | AGL2012-39597-C02-02 | |
dc.relation.projectID | MAT2012-35556 | |
dc.relation.projectID | CSO2010-11384-E | |
dc.relation.projectID | PROMETEO/2009/016 | |
dc.rights.accessRights | restricted access | |
dc.subject.cdu | 546 | |
dc.subject.keyword | biomaterial | |
dc.subject.keyword | enzyme-driven | |
dc.subject.keyword | controlled release | |
dc.subject.keyword | mesoporous silica nanoparticles | |
dc.subject.keyword | 3D scaffolds | |
dc.subject.ucm | Química inorgánica (Química) | |
dc.subject.unesco | 2303 Química Inorgánica | |
dc.title | Towards the development of smart 3D “gated scaffolds” for on-command delivery | |
dc.type | journal article | |
dc.volume.number | 10 | |
dspace.entity.type | Publication | |
relation.isAuthorOfPublication | d92c7075-3d31-45ec-a18d-35a5010ee8e1 | |
relation.isAuthorOfPublication | 14ed7f4d-b114-4a3c-9d8c-83f05fbfc703 | |
relation.isAuthorOfPublication | 93c09e60-0b6e-49bf-a0aa-bc7a08319f34 | |
relation.isAuthorOfPublication | 791023b8-2531-44eb-ba01-56e3b7caa0cb | |
relation.isAuthorOfPublication.latestForDiscovery | 14ed7f4d-b114-4a3c-9d8c-83f05fbfc703 |
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