Mechanochemical Synthesis of Primary Amides

Simple item page
dc.contributor.authorGómez-Carpintero Jiménez, Jorge
dc.contributor.authorSánchez Cebrián, Juan Domingo
dc.contributor.authorGonzález Matilla, Juan Francisco
dc.contributor.authorMenéndez Ramos, José Carlos
dc.date.accessioned2023-06-16T14:18:17Z
dc.date.available2023-06-16T14:18:17Z
dc.date.issued2021-10-01
dc.descriptionCRUE-CSIC (Acuerdos Transformativos 2021)
dc.description.abstractBall milling of aromatic, heteroaromatic, vinylic, and aliphatic esters with ethanol and calcium nitride afforded the corresponding primary amides in a transformation that was compatible with a variety of functional groups and maintained the integrity of a stereocenter α to carbonyl. This methodology was applied to α-amino esters and N-BOC dipeptide esters and also to the synthesis of rufinamide, an antiepileptic drug.en
dc.description.departmentDepto. de Química en Ciencias Farmacéuticas
dc.description.facultyFac. de Farmacia
dc.description.refereedTRUE
dc.description.sponsorshipMinisterio de Ciencia, Innovación y Universidades (España)
dc.description.sponsorshipCooperación Europea en el Campo de la Investigación Científica y Técnica
dc.description.statuspub
dc.eprint.idhttps://eprints.ucm.es/id/eprint/69344
dc.identifier.citationGómez-Carpintero Jiménez, J., Sánchez Cebrián, J. D., González Matilla, J. F. & Menéndez Ramos, J. C. «Mechanochemical Synthesis of Primary Amides». The Journal of Organic Chemistry, vol. 86, n.o 20, octubre de 2021, pp. 14232-37. DOI.org (Crossref), https://doi.org/10.1021/acs.joc.1c02350.
dc.identifier.doi10.1021/acs.joc.1c02350
dc.identifier.issn0022-3263
dc.identifier.officialurlhttps://doi.org/10.1021/acs.joc.1c02350
dc.identifier.relatedurlhttps://pubs.acs.org/doi/abs/10.1021/acs.joc.1c02350
dc.identifier.urihttps://hdl.handle.net/20.500.14352/4599
dc.issue.number20
dc.journal.titleThe Journal of Organic Chemistry
dc.language.isoeng
dc.page.final14237
dc.page.initial14232
dc.publisherACS Publications
dc.relation.projectID(RTI2018-097662-B-I00)
dc.relation.projectIDCOST Action CA18112
dc.rightsAtribución 3.0 España
dc.rights.accessRightsopen access
dc.rights.urihttps://creativecommons.org/licenses/by/3.0/es/
dc.subject.ucmQuímica orgánica (Química)
dc.subject.unesco2306 Química Orgánica
dc.titleMechanochemical Synthesis of Primary Amides
dc.typejournal article
dc.volume.number86
dspace.entity.typePublication
relation.isAuthorOfPublicationb317919e-1036-4ccc-b8c0-f3e06ffdfec5
relation.isAuthorOfPublication2fac9923-9d2b-459a-b51e-28736c9abe0b
relation.isAuthorOfPublicatione321e67a-fc49-4215-8fa2-538c7924cb7c
relation.isAuthorOfPublication4c8ca147-677d-4846-97b7-d4419662ff60
relation.isAuthorOfPublication.latestForDiscoveryb317919e-1036-4ccc-b8c0-f3e06ffdfec5

Download

Original bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
acs.joc.1c02350.pdf
Size:
1.4 MB
Format:
Adobe Portable Document Format
Download Download

Collections

Artículos