Mechanochemical Synthesis of Primary Amides
| dc.contributor.author | Gómez-Carpintero Jiménez, Jorge | |
| dc.contributor.author | Sánchez Cebrián, Juan Domingo | |
| dc.contributor.author | González Matilla, Juan Francisco | |
| dc.contributor.author | Menéndez Ramos, José Carlos | |
| dc.date.accessioned | 2023-06-16T14:18:17Z | |
| dc.date.available | 2023-06-16T14:18:17Z | |
| dc.date.issued | 2021-10-01 | |
| dc.description | CRUE-CSIC (Acuerdos Transformativos 2021) | |
| dc.description.abstract | Ball milling of aromatic, heteroaromatic, vinylic, and aliphatic esters with ethanol and calcium nitride afforded the corresponding primary amides in a transformation that was compatible with a variety of functional groups and maintained the integrity of a stereocenter α to carbonyl. This methodology was applied to α-amino esters and N-BOC dipeptide esters and also to the synthesis of rufinamide, an antiepileptic drug. | en |
| dc.description.department | Depto. de Química en Ciencias Farmacéuticas | |
| dc.description.faculty | Fac. de Farmacia | |
| dc.description.refereed | TRUE | |
| dc.description.sponsorship | Ministerio de Ciencia, Innovación y Universidades (España) | |
| dc.description.sponsorship | Cooperación Europea en el Campo de la Investigación Científica y Técnica | |
| dc.description.status | pub | |
| dc.eprint.id | https://eprints.ucm.es/id/eprint/69344 | |
| dc.identifier.citation | Gómez-Carpintero Jiménez, J., Sánchez Cebrián, J. D., González Matilla, J. F. & Menéndez Ramos, J. C. «Mechanochemical Synthesis of Primary Amides». The Journal of Organic Chemistry, vol. 86, n.o 20, octubre de 2021, pp. 14232-37. DOI.org (Crossref), https://doi.org/10.1021/acs.joc.1c02350. | |
| dc.identifier.doi | 10.1021/acs.joc.1c02350 | |
| dc.identifier.issn | 0022-3263 | |
| dc.identifier.officialurl | https://doi.org/10.1021/acs.joc.1c02350 | |
| dc.identifier.relatedurl | https://pubs.acs.org/doi/abs/10.1021/acs.joc.1c02350 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14352/4599 | |
| dc.issue.number | 20 | |
| dc.journal.title | The Journal of Organic Chemistry | |
| dc.language.iso | eng | |
| dc.page.final | 14237 | |
| dc.page.initial | 14232 | |
| dc.publisher | ACS Publications | |
| dc.relation.projectID | (RTI2018-097662-B-I00) | |
| dc.relation.projectID | COST Action CA18112 | |
| dc.rights | Atribución 3.0 España | |
| dc.rights.accessRights | open access | |
| dc.rights.uri | https://creativecommons.org/licenses/by/3.0/es/ | |
| dc.subject.ucm | Química orgánica (Química) | |
| dc.subject.unesco | 2306 Química Orgánica | |
| dc.title | Mechanochemical Synthesis of Primary Amides | |
| dc.type | journal article | |
| dc.volume.number | 86 | |
| dspace.entity.type | Publication | |
| relation.isAuthorOfPublication | b317919e-1036-4ccc-b8c0-f3e06ffdfec5 | |
| relation.isAuthorOfPublication | 2fac9923-9d2b-459a-b51e-28736c9abe0b | |
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| relation.isAuthorOfPublication | 4c8ca147-677d-4846-97b7-d4419662ff60 | |
| relation.isAuthorOfPublication.latestForDiscovery | b317919e-1036-4ccc-b8c0-f3e06ffdfec5 |
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