Infección nosocomial en pacientes sometidos a reconstrucción con trasplante de tejido libre microvascularizado en el tratamiento de patología de cabeza y cuello
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2025
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05/07/2024
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Universidad Complutense de Madrid
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Abstract
Los colgajos libres microvascularizados son el método reconstructivo de elección para defectos tridimensionalmente complejos en cabeza y cuello. Su finalidad es restaurar la funcionalidad y la anatomía comprometidas tras resecciones tumorales, secuelas traumáticas, infecciosas o congénitas, específicas para cada localización (cavidad oral, orofaringe, piel y partes blandas, base de cráneo y senos paranasales).Las neoplasias malignas, particularmente el carcinoma de células escamosas en estadios avanzados, constituyen la patología más común entre las reconstrucciones microquirúrgicas. La recuperación temprana después de la cirugía es fundamental para el pronóstico oncológico, ya que la mayoría de los pacientes requerirán tratamiento adyuvante con radioterapia, el cual debe iniciarse en las primeras siete semanas...
Nowadays, microvascular free-flap surgery is considered the ‘gold standard’ for the reconstruction of extensive three-dimensional defects on the head and neck. The aim is to restore function and compromised anatomy following tumour resections, traumatic, infectious, or congenital sequelae, which are specific to each area (oral cavity, oropharynx, skin and soft tissues, skull base and paranasal sinuses).Malignancies, especially squamous cell carcinoma of the head and neck in advanced stages, are the most common condition in microsurgical reconstructions. Early recovery after surgery is critical for cancer prognosis, as most patients will require adjuvant treatment with radiotherapy, which should be started within the first seven weeks...
Nowadays, microvascular free-flap surgery is considered the ‘gold standard’ for the reconstruction of extensive three-dimensional defects on the head and neck. The aim is to restore function and compromised anatomy following tumour resections, traumatic, infectious, or congenital sequelae, which are specific to each area (oral cavity, oropharynx, skin and soft tissues, skull base and paranasal sinuses).Malignancies, especially squamous cell carcinoma of the head and neck in advanced stages, are the most common condition in microsurgical reconstructions. Early recovery after surgery is critical for cancer prognosis, as most patients will require adjuvant treatment with radiotherapy, which should be started within the first seven weeks...
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Tesis inédita de la Universidad Complutense de Madrid, Facultad de Medicina, leída el 05-07-2024