Organización Sináptica de la Corteza Entorrinal Humana
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2025
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11/03/2025
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Universidad Complutense de Madrid
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Abstract
La formación y consolidación de la memoria declarativa requiere de la interacción de múltiples áreas cerebrales, que dan lugar a una rica red de comunicación. Entre ellas, la conectividad entre la corteza entorrinal y el hipocampo representa un elemento principal en esta comunicación. La corteza entorrinal es esencial en los procesos de memoria y orientación espacial, actuando como un interfaz sensorial y mediando el flujo de información entre el hipocampo y la neocorteza. Además, diferentes estudios han relacionado la corteza entorrinal con varias enfermedades neurodegenerativas, como la enfermedad de Alzheimer...
The formation and consolidation of declarative memories require the interaction of rich networks that encompass multiple brain areas. Among them, the entorhinal-hippocampal connectivity is a key element. The entorhinal cortex plays a pivotal role in memory function and spatial navigation, acting as a major sensory interface and mediating the flow of information between the hippocampus and the neocortex. In addition, several studies have linked major neurodegenerative disorders, such as Alzheimer’s disease, to alterations in the entorhinal cortex...
The formation and consolidation of declarative memories require the interaction of rich networks that encompass multiple brain areas. Among them, the entorhinal-hippocampal connectivity is a key element. The entorhinal cortex plays a pivotal role in memory function and spatial navigation, acting as a major sensory interface and mediating the flow of information between the hippocampus and the neocortex. In addition, several studies have linked major neurodegenerative disorders, such as Alzheimer’s disease, to alterations in the entorhinal cortex...
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Tesis inédita de la Universidad Complutense de Madrid, Facultad de Ciencias Biológicas, leída el 11-03-2025