Heart Failure Is a Poor Prognosis Risk Factor in Patients Undergoing Cholecystectomy: Results from a Spanish Data-Based Analysis

dc.contributor.authorMarco Martínez, Javier
dc.contributor.authorElola Somoza, Francisco Javier
dc.contributor.authorFernández Pérez, Cristina
dc.contributor.authorBernal Sobrino, José Luis
dc.contributor.authorAzaña Gómez, Francisco Javier
dc.contributor.authorGarcía Klepizg, José Luis
dc.contributor.authorAndrès, Emmanuel
dc.contributor.authorZapatero Gaviria, Antonio
dc.contributor.authorBarba Martín, Raquel
dc.contributor.authorCalvo Manuel, Elpidio
dc.contributor.authorCanora Lebrato, Jesus
dc.contributor.authorLorenzo Villalba, Noel
dc.contributor.authorMéndez Bailón, Manuel
dc.date.accessioned2023-06-17T08:23:59Z
dc.date.available2023-06-17T08:23:59Z
dc.date.issued2021-04-16
dc.description.abstractBackground: The incidence of cholecystectomy is increasing as the result of the aging worldwide. Our aim was to determine the influence of heart failure on in-hospital outcomes in patients undergoing cholecystectomy in the Spanish National Health System (SNHS). Methods: We conducted a retrospective study using the Spanish National Hospital Discharge Database. Patients older than 17 years undergoing cholecystectomy in the period 2007–2015 were included. Demographic and administrative variables related to patients’ diseases as well as procedures were collected. Results: 478,111 episodes of cholecystectomy were identified according to the data from SNHS hospitals in the period evaluated. From all the episodes, 3357 (0.7%) were excluded, as the result the sample was represented by 474,754 episodes. Mean age was 58.3 (+16.5) years, and 287,734 (60.5%) were women (p < 0.001). A primary or secondary diagnosis of HF was identified in 4244 (0.89%) (p < 0.001) and mean age was 76.5 (+9.6) years. A higher incidence of all main complications studied was observed in the HF group (p < 0.001), except stroke (p = 0.753). Unadjusted in-hospital mortality was 1.1%, 12.9% in the group with HF versus 1% in the non HF group (p < 0.001). Average length of hospital stay was 5.4 (+8.9) days, and was higher in patients with HF (16.2 + 17.7 vs. 5.3 + 8.8; p < 0.001). Risk-adjusted in-hospital mortality models’ discrimination was high in both cases, with AUROC values = 0.963 (0.960–0.965) in the APRG-DRG model and AUROC = 0.965 (0.962–0.968) in the CMS adapted model. Median odds ratio (MOR) was high (1.538 and 1.533, respectively), stating an important variability of risk-adjusted outcomes among hospitals. Conclusions: The presence of HF during admission increases in hospital mortality and lengthens the hospital stay in patients undergoing cholecystectomy. However, mortality and hospital stay have significantly decreased during the study period in both groups (HF and non HF patients).
dc.description.departmentDepto. de Medicina
dc.description.facultyFac. de Medicina
dc.description.refereedTRUE
dc.description.statuspub
dc.eprint.idhttps://eprints.ucm.es/id/eprint/71308
dc.identifier.doi10.3390/jcm10081731
dc.identifier.issn2077-0383
dc.identifier.officialurlhttps://doi.org/10.3390/jcm10081731
dc.identifier.relatedurlhttps://www.mdpi.com/2077-0383/10/8/1731/htm
dc.identifier.urihttps://hdl.handle.net/20.500.14352/6966
dc.issue.number8
dc.journal.titleJournal of Clinical Medicine
dc.language.isoeng
dc.page.initial1731
dc.publisherMPDI
dc.rightsAtribución 3.0 España
dc.rights.accessRightsopen access
dc.rights.urihttps://creativecommons.org/licenses/by/3.0/es/
dc.subject.keywordheart failure
dc.subject.keywordcholecystectomy surgery
dc.subject.keywordin-hospital outcomes
dc.subject.keywordlength of stay
dc.subject.ucmAtención primaria y medicina de familia
dc.subject.ucmCardiología
dc.subject.unesco3205.01 Cardiología
dc.titleHeart Failure Is a Poor Prognosis Risk Factor in Patients Undergoing Cholecystectomy: Results from a Spanish Data-Based Analysis
dc.typejournal article
dc.volume.number10
dspace.entity.typePublication
relation.isAuthorOfPublication42d41152-c320-491e-81de-2f601b12e9d8
relation.isAuthorOfPublicatione3b551e4-0127-4a0e-ad9e-2232be67b78b
relation.isAuthorOfPublication82609182-d105-446f-b580-243bb0b8f40b
relation.isAuthorOfPublication9635ebaf-1e70-4b67-9ba8-903104a39d00
relation.isAuthorOfPublication.latestForDiscovery42d41152-c320-491e-81de-2f601b12e9d8
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