Management and outcome of liver abscesses after liver transplantation

Simple item page
dc.contributor.authorJusto Alonso, Iago
dc.contributor.authorJiménez Romero, Luis Carlos
dc.contributor.authorManrique Municio, Alejandro
dc.contributor.authorCaso Maestro, Óscar
dc.contributor.authorCalvo Pulido, Jorge
dc.contributor.authorCambra Molero, Félix
dc.contributor.authorMarcacuzco Quinto, Alberto Alejandro
dc.date.accessioned2024-02-05T10:57:25Z
dc.date.available2024-02-05T10:57:25Z
dc.date.issued2018-04-09
dc.description.abstractBackground: Liver abscess after orthotopic liver transplantation (OLT) is a rare, life-threatening complication. The aim of this study is to analyze the incidence, risk factors, clinical manifestations, treatment and outcomes of liver abscesses after OLT. Methods: We perform a retrospective review of the patients who developed one or more liver abscesses among a series of 984 patients who underwent OLT between January 2000 and December 2016. Results: Fourteen patients (1.5%) developed 18 episodes of liver abscesses, and the median time from OLT to the diagnosis of liver abscess was 39.7 months. Major predisposing factors were biliary strictures in 11 patients, hepatic artery thrombosis in 8, re-OLT in 3, choledochojejunostomy in 2, living donor OLT in 2, donor after cardiac death in 1, split liver in 1, and liver biopsy in 1. All patients were managed by intravenous antibiotics; percutaneous drainage was performed in 10 patients, while 2 patients underwent re-OLT. The mortality rate related to liver abscesses was 21.4%. The mean hospital stay was 30 ± 19 days, and during a mean follow-up of 93 ± 78 months, three other patients died. Conclusions: Liver abscesses must be managed with antibiotic therapy and percutaneous drainage, but when these conservative measures fail (persistent abscess and sepsis), a re-OLT must be performed in order to prevent the high mortality associated with this severe complication.
dc.description.departmentDepto. de Cirugía
dc.description.facultyFac. de Medicina
dc.description.refereedTRUE
dc.description.statuspub
dc.identifier.citationJusto I, Jiménez-Romero C, Manrique A, Caso O, Calvo J, Cambra F, Marcacuzco A. Management and Outcome of Liver Abscesses After Liver Transplantation. World J Surg. 2018 Oct;42(10):3341-3349. doi: 10.1007/s00268-018-4622-x
dc.identifier.doi10.1007/s00268-018-4622-x.
dc.identifier.issn0364-2313
dc.identifier.officialurlhttps://onlinelibrary.wiley.com/doi/10.1007/s00268-018-4622-x
dc.identifier.relatedurlhttps://pubmed.ncbi.nlm.nih.gov/29633100/
dc.identifier.urihttps://hdl.handle.net/20.500.14352/98801
dc.issue.number10
dc.journal.titleWorld Journal of Surgery
dc.language.isoeng
dc.page.final3349
dc.page.initial3341
dc.publisherWiley
dc.rights.accessRightsrestricted access
dc.subject.cdu617
dc.subject.ucmCirugía
dc.subject.unesco3213 Cirugía
dc.titleManagement and outcome of liver abscesses after liver transplantation
dc.typejournal article
dc.type.hasVersionVoR
dc.volume.number42
dspace.entity.typePublication
relation.isAuthorOfPublication8060a748-5de0-4268-b1b8-c289509aa978
relation.isAuthorOfPublicationb1cb0014-c38c-486f-adde-38e92e705674
relation.isAuthorOfPublication2ed3b594-c3f6-4780-ab8c-93872b0b7d83
relation.isAuthorOfPublicationc64d5a67-c9bb-40ab-a738-b753b75660fa
relation.isAuthorOfPublication03b8bd3e-f1e8-4b08-b636-edc56135909b
relation.isAuthorOfPublicationb7c4adec-5246-4ef3-8dfb-acc9db45054b
relation.isAuthorOfPublication333cc96d-8ba3-4109-bd9f-a70dd7c69507
relation.isAuthorOfPublication.latestForDiscovery8060a748-5de0-4268-b1b8-c289509aa978
Download
Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
Management and Outcome.pdf
Size:
397.34 KB
Format:
Adobe Portable Document Format
Download
Collections
Artículos