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Plazomicin activity against 346 extended-spectrum-beta-lactamase/AmpC producing Escherichia coli urinary isolates in relation to aminoglycoside-modifying enzymes

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dc.contributor.authorLópez Díaz, María Carmen
dc.contributor.authorCulebras López, Esther
dc.contributor.authorRodríguez-Avial Infante, Iciar
dc.contributor.authorRíos Dueñas, Esther
dc.contributor.authorViñuela Prieto, José Manuel
dc.contributor.authorPicazo De La Garza, Juan José
dc.contributor.authorRodríguez-Avial López-Doriga, Carmen
dc.date.accessioned2024-12-17T09:16:27Z
dc.date.available2024-12-17T09:16:27Z
dc.date.issued2016
dc.descriptionNational R&D Plan, AES 2013
dc.description.abstractThe activity of plazomicin and clinically relevant aminoglycosides was tested against 346 extended-spectrum-β-lactamase/AmpC-producing Escherichia coli urinary isolates, and the results were correlated with the presence of aminoglycoside-modifying enzymes (AMEs). Data showed that plazomicin was very active against all ESBL/AmpC-producing E. coli urinary isolates. Its activity was not related to the AME genes studied.
dc.description.departmentDepto. de Medicina
dc.description.facultyFac. de Medicina
dc.description.refereedTRUE
dc.description.sponsorshipInstituto de Salud Carlos III
dc.description.sponsorshipEuropean Commission
dc.description.statuspub
dc.identifier.citationLópez-Diaz MDC, Culebras E, Rodríguez-Avial I, Rios E, Viñuela-Prieto JM, Picazo JJ, Rodríguez-Avial C. 2017. Plazomicin Activity against 346 Extended-Spectrum-β-Lactamase/AmpC-Producing Escherichia coli Urinary Isolates in Relation to Aminoglycoside-Modifying Enzymes. Antimicrob Agents Chemother 61:10.1128/aac.02454-16. https://doi.org/10.1128/aac.02454-16
dc.identifier.doi10.1128/AAC.02454-16
dc.identifier.essn1098-6596
dc.identifier.issn0066-4804
dc.identifier.officialurlhttps://doi.org/10.1128/aac.02454-16
dc.identifier.relatedurlhttps://journals.asm.org/doi/10.1128/aac.02454-16
dc.identifier.urihttps://hdl.handle.net/20.500.14352/112723
dc.issue.number2
dc.journal.titleAntimicrobial Agents and Chemotherapy
dc.language.isospa
dc.publisherAmerican Society for Microbiology
dc.relation.projectIDPI13/01471
dc.rights.accessRightsrestricted access
dc.subject.cdu579.61
dc.subject.keywordAMEs
dc.subject.keywordESBL
dc.subject.keywordEscherichia coli
dc.subject.keywordplazomicin
dc.subject.keywordaminoglycosides
dc.subject.ucmCiencias Biomédicas
dc.subject.unesco3201.03 Microbiología Clínica
dc.titlePlazomicin activity against 346 extended-spectrum-beta-lactamase/AmpC producing Escherichia coli urinary isolates in relation to aminoglycoside-modifying enzymes
dc.typejournal article
dc.type.hasVersionVoR
dc.volume.number61
dspace.entity.typePublication
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relation.isAuthorOfPublication.latestForDiscoverya2bc4d93-7fe5-4d3b-a65c-f29fe5c2b853

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