Synthesis of Enantiopure Allylamines by Reductive Alkylation of Amino Epoxides with Organolithium Reagents
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2005
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American Chemical Society
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Concellón, José M., et al. «Synthesis of Enantiopure Allylamines by Reductive Alkylation of Amino Epoxides with Organolithium Reagents». Organic Letters, vol. 8, n.o 2, enero de 2006, pp. 349-51. DOI.org (Crossref), https://doi.org/10.1021/ol0529602.
Abstract
Transformation of enantiopure (2R,1‘S)-2-(1-aminoalkyl)epoxides into the corresponding allylamines is described. The opening of the epoxide ring with different organolithium compounds takes place with total selectivity and in high yields.