Strengthening the relationship between intractable plantar keratosis and human papillomavirus

Simple item page
dc.contributor.authorAlou Cervera, Luis
dc.contributor.authorBecerro De Bengoa Vallejo, Ricardo
dc.contributor.authorLosa Iglesias, Marta Elena
dc.contributor.authorMoreno, Juan
dc.contributor.authorSánchez Gómez, Rubén
dc.contributor.authorGonzález Hidalgo, Natalia
dc.contributor.authorSevillano Fernández, David
dc.date.accessioned2024-02-02T07:30:57Z
dc.date.available2024-02-02T07:30:57Z
dc.date.issued2024-01-31
dc.description.abstractThe aim of the study was to determine the presence of human papillomavirus (HPV) in patients with intractable plantar keratosis (IPK) by comparing the histopathological findings of biopsies. A prospective, observational, and concordance study was carried out. Three different specimens were taken from each IPK. A first punch was sent for histopathological examination, and a second punch and a superficial skin scraping were both sent for HPV  polymerase chain reaction (PCR) and type determination. A total of 51 patients were included. From the histopathological examination, it was determined that 35 (68.6%) samples were diagnosed as warts and 16 (31.3%) as keratosis. However, the presence of HPV was confirmed by PCR in 49 (96.1%) and in 42 (82.4%) samples obtained by punch and superficial scraping, respectively. In the 49 PCR‐positive samples, the most common HPV types were HPV1, HPV2, HPV27, HPV57, and HPV65, accounting for 81.6% of the samples. In conclusion, this study demonstrates that HPV infection and IPK lesions are very closely related. Although we cannot confirm that HPV is the cause of the development of IPK, the high prevalence of HPV observed in these lesions calls for a change to the procedures for managing IPK.
dc.description.departmentDepto. de Medicina
dc.description.facultyFac. de Medicina
dc.description.refereedTRUE
dc.description.statuspub
dc.identifier.citationAlou L, Becerro-de-Bengoa-Vallejo R, Losa-Iglesias ME, Moreno J, Sánchez-Gómez R, González N, Sevillano D. Strengthening the relationship between intractable plantar keratosis and human papillomavirus. J Med Virol. 2024 Feb;96(2):e29431.
dc.identifier.doi10.1002/jmv.29431
dc.identifier.issn0146-6615
dc.identifier.issn1096-9071
dc.identifier.officialurlhttps://onlinelibrary.wiley.com/doi/10.1002/jmv.29431
dc.identifier.relatedurlhttps://pubmed.ncbi.nlm.nih.gov/38293752/
dc.identifier.urihttps://hdl.handle.net/20.500.14352/98030
dc.issue.number2
dc.journal.titleJournal of Medical Virology
dc.language.isoeng
dc.page.initiale29431
dc.publisherWiley
dc.rightsAttribution 4.0 Internationalen
dc.rights.accessRightsopen access
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subject.cdu579
dc.subject.keywordHistopathology
dc.subject.keywordHuman papillomavirus
dc.subject.keywordIntractable plantar keratosis
dc.subject.keywordPCR
dc.subject.keywordPunch
dc.subject.keywordScraping
dc.subject.ucmEnfermería, Fisioterapia y Podología
dc.subject.unesco2414 Microbiología
dc.titleStrengthening the relationship between intractable plantar keratosis and human papillomavirus
dc.typejournal article
dc.type.hasVersionVoR
dc.volume.number96
dspace.entity.typePublication
relation.isAuthorOfPublication889e4dc3-c630-429e-be0f-7f0df2cff492
relation.isAuthorOfPublicationbbd621a9-7baf-481a-83c7-124287192d07
relation.isAuthorOfPublicationdc143899-0041-4a0f-8dd2-d696077ec375
relation.isAuthorOfPublication41cae2d7-0146-4705-b653-a302a81db4d0
relation.isAuthorOfPublication518c916a-df78-48cc-9bf7-6a2aaca7d6a2
relation.isAuthorOfPublication.latestForDiscovery889e4dc3-c630-429e-be0f-7f0df2cff492
Download
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Journal of Medical Virology - 2024 - Alou - Strengthening the relationship between intractable plantar keratosis and human.pdf
Size:
1.1 MB
Format:
Adobe Portable Document Format
downoload Download
Collections
Artículos