Forward-scattered and backward-scattered light in moderate keratoconus

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dc.contributor.authorVillanueva Gómez-Chacón, Celia
dc.contributor.authorViviano, Francesco
dc.contributor.authorGarcía Montero, María
dc.contributor.authorLorente Velázquez, Amalia
dc.contributor.authorMartínez Alberquilla, Irene
dc.contributor.authorGarzón Jiménez, Nuria
dc.date.accessioned2023-06-22T12:43:15Z
dc.date.available2023-06-22T12:43:15Z
dc.date.issued2023-03-15
dc.descriptionVersion of Record online: 15 March 2023; Manuscript accepted: 01 March 2023; Manuscript revised: 17 February 2023; Manuscript received: 20 October 2022
dc.description.abstractIntroduction: To evaluate the backscattered light, objective scatter index (OSI) and retinal straylight in patients with moderate keratoconus and healthy control subjects. Methods: A prospective observational study was developed with 33 patients in the moderate-keratoconus group (KC) and 34 in the non-keratoconus group (NKC). Corneal densitometry was obtained using Scheimpflug corneal tomography and measurements were expressed in grayscale units (GSU) over four zones within a 12.00 mm diameter around the corneal apex. A straylight meter was used to determine the amount of intraocular straylight under scotopic conditions, and the straylight parameter (LOG(s)) and test duration were recorded. The Optical Quality Analysis System based on the double-pass technique determined the OSI value. Results: Significant differences were observed between the KC and NKC groups for corneal densitometry (except in the 6–10 mm zone), OSI and retinal straylight. A moderate and significant correlation was found between OSI and retinal straylight LOG(s) (r = 0.52, p = 0.002). Weaker and non-significant correlations were found between corneal densitometry and the other parameters analysed (i.e., OSI, retinal straylight LOG(s) and retinal straylight times). Conclusions: Backscattered light, retinal straylight and the OSI show clear differences between healthy eyes and those with moderate KC. The changes present in the stages of KC evaluated in the current study (stages II and III according to the Amsler–Krumeich classification) might alter the scattering of the light entering the eye.
dc.description.departmentDepto. de Optometría y Visión
dc.description.facultyFac. de Óptica y Optometría
dc.description.refereedTRUE
dc.description.sponsorshipUniversidad Complutense de Madrid (España)
dc.description.sponsorshipBanco Santander (España)
dc.description.statuspub
dc.eprint.idhttps://eprints.ucm.es/id/eprint/77029
dc.identifier.doi10.1111/opo.13126
dc.identifier.issn0275-5408
dc.identifier.officialurlhttps://doi.org/10.1111/opo.13126
dc.identifier.urihttps://hdl.handle.net/20.500.14352/73093
dc.journal.titleOphthalmic and Physiological Optics
dc.language.isoeng
dc.page.initial8 p.
dc.publisherWILEY-BLACKWELL Publishing
dc.relation.projectIDCT63/19-CT64/19
dc.rightsAtribución-NoComercial-SinDerivadas 3.0 España
dc.rights.accessRightsopen access
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/3.0/es/
dc.subject.cdu617.713-007
dc.subject.cdu617.735-007
dc.subject.keywordBackward scattering
dc.subject.keywordCorneal densitometry
dc.subject.keywordForward scattering
dc.subject.keywordKeratoconus
dc.subject.keywordRetinal straylight
dc.subject.ucmOftalmología
dc.subject.ucmAnatomía ocular
dc.subject.ucmÓptica fisiológica
dc.subject.unesco3201.09 Oftalmología
dc.titleForward-scattered and backward-scattered light in moderate keratoconus
dc.typejournal article
dspace.entity.typePublication
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relation.isAuthorOfPublication.latestForDiscovery9b637d56-481e-40c6-a0e6-eb4de92e663c
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