Publication: Analysis of the influence of the cell geometry, orientation and cell proximity effects on the electric field distribution from direct RF exposure
Full text at PDC
Advisors (or tutors)
IOP Publishing Ltd
This paper shows the importance of using a cell model with the proper geometry, orientation and internal structure to study possible cellular effects from direct radiofrequency exposure. For this purpose, the electric field intensity is calculated, using the finite element numerical technique, in single-and multilayer spherical, cylindrical and ellipsoidal mammalian cell models exposed to linearly polarized electromagnetic plane waves of frequencies 900 and 2450 MHz. An extensive analysis is performed on the influence that the cell geometry and orientation with respect to the external field have in the value of the electric field induced in the membrane and cytoplasm. We also show the significant role that the cytoplasmic and extracellular bound water layers play in determining the electric field intensity for the cylindrical and ellipsoidal cell models. Finally, a study of the mutual interactions between cells shows that polarizing effects between cells significantly modify the values of field intensity within the cell.
© 2001, IOP Publishing Ltd. This work has been sponsored by the Comunidad Autónoma de Madrid, project 08.8/0002/1997.
 Adey, W.R., Byus, C.V., Cain, C.D., Higgins, R.J., Jones, R.A., Kean, C.J., Kuster, N., MacMurray, A., Stagg, R.B., Zimmerman, G., 2000, Spontaneous and nitrosourea-induced primary tumors of the central nervous system in Fischer 344 rats chronically exposed to frequency modulated microwaves fields, Cancer Res., 60, 1857–63.  Adey, W.R., et al., 1999, Spontaneous and nitrosourea-induced primary tumors of the central nervous system in Fischer 344 rats chronically exposed to 836 MHz modulated microwaves, Radiat Res., 152, 293–302.  Asami, K., Hanai, T., Koizumi, N., 1980, Dielectric approach to suspension of ellipsoidal particles covered with a shell in particular reference to biological cells, Japan. J. Appl. Phys., 19, 359–65.  Bernardi, P., Cavagnaro, M., d’Inzeo, Liberti M., 1998, A cell model to evaluate EM field absorption in biological samples: a sensitivity and relevance analysis, Proc. 4th EBEA Congress (Zagreb, Croatia), pp 129–30. ——1999, Cell modeling to evaluate EM field absorption in biological samples, URSI XXVI General Assembly (Toronto), p. 616.  Drago, G.P., Ridella, S., 1982, Evaluation of electrical fields inside a biological structure, Br. J. Cancer, 45, 215–19.  Gabriel, S., Lau, R., Wand, Gabriel C., 1996, The dielectric properties of biological tissues: III. Parametric models for the dielectric spectrum of tissues, Phys. Med. Biol., 41, 2271–93.  Gandhi, O.P., 1974, A method of measuring RF absorption of whole animals and bodies of prolate spheroidal shapes, Proc. Microwave Power Symp. (Milwaukee, WI: University of Milwaukee), pp 28–31.  Giner, V., Sancho, M., Lee, R.S., Martínez, G., Pethig, R., 1999, Transverse dipolar chaining in binary suspensions induced by RF fields, J. Phys. D: Appl. Phys., 32, 1182–6.  Johnson, C.C., Durney, C.H., Massoudi, H., 1975, Long wavelength electromagnetic power absorption in prolate spheroidal models of man and animals, IEEE Trans. Microwave Theory Tech., 20, 739–47.  Lin, J.C., Guy, A.W., Johnson, C.C., 1975, Power deposition in a spherical model of man exposed to 1–20 MHz electromagnetic fields, IEEE Trans Microwave Theory Tech., 23, 246–53.  Liu, L.M., Cleary, S.F., 1995, Absorbed energy distribution from radiofrequency electromagnetic radiation in mammalian cell model: effect of membrane-bound water, Bioelectromagnetics, 16, 160–71.  Malyapa, R.S., Ahern, E.W., Straube,W.L.,Moros, E.G., Pickard,W.F., Roti Roti, J.L., 1997, Measurement of DNA damage after exposure to electromagnetic radiation in the cellular phone communication frequency band (835.62 and 847.74 MHz), Radiat Res., 148, 618–927.  Miller, R.D., Jones, T.B., 1993, Electro orientation of ellipsoidal erythrocytes, Biophys. J., 64, 1588–95.