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Associations between vitamin D receptor (VDR) polymorphisms and gut microbiota in a spanish population sample

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dc.conference.date1-15 Nov 2023
dc.conference.placeEvento online
dc.conference.title3rd International Electronic Conference on Nutrients
dc.contributor.authorGonzález Soltero, Rocío
dc.contributor.authorBressa, Carlo
dc.contributor.authorTabone, Mariangela
dc.contributor.authorClemente, Sara
dc.contributor.authorLarrosa Pérez, María Del Mar
dc.contributor.authorBailén, María
dc.date.accessioned2024-05-29T16:16:11Z
dc.date.available2024-05-29T16:16:11Z
dc.date.issued2023-10-31
dc.description2023 Descuento MDPI
dc.description.abstractThis study examined the association between genetic variations in the Vitamin D Receptor (VDR) gene and the composition of gut microbiota in a Spanish population. The VDR gene plays a role in mediating the effects of vitamin D on gut microbiota composition. We analyzed 87 healthy participants from the Spanish Caucasian population and found that the genetic variations were in Hardy–Weinberg equilibrium. Through metataxonomic sequencing, we identified that the GG genotype from the VDR polymorphism rs731236 seems to be associated with the opportunistic genus Solobacterium, indicating that genetic variations may influence the composition of gut microbiota.
dc.description.departmentDepto. de Nutrición y Ciencia de los Alimentos
dc.description.facultyFac. de Farmacia
dc.description.fundingtypeDescuento UCM
dc.description.refereedTRUE
dc.description.sponsorshipUniversidad Europea de Madrid
dc.description.statuspub
dc.identifier.citationGonzález Soltero R, Bressa C, Tabone M, Clemente S, Larrosa M, Bailén M. Associations between Vitamin D Receptor (VDR) Polymorphisms and Gut Microbiota in a Spanish Population Sample. Biology and Life Sciences Forum. 2023; 29(1):4
dc.identifier.doi10.3390/iecn2023-15530
dc.identifier.officialurlhttps://doi.org/10.3390/IECN2023-15530
dc.identifier.relatedurlhttps://www.mdpi.com/2673-9976/29/1/4
dc.identifier.urihttps://hdl.handle.net/20.500.14352/104556
dc.language.isoeng
dc.page.final6
dc.page.initial1
dc.relation.projectID2018/UEM04
dc.rightsAttribution 4.0 Internationalen
dc.rights.accessRightsopen access
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subject.cdu575(075.8)
dc.subject.cdu579.61(075.8)
dc.subject.keywordVitamin D Receptor (VDR) polymorphisms
dc.subject.keywordGut microbiota
dc.subject.keywordSpanish population
dc.subject.keywordrs2731236
dc.subject.keywordLefse
dc.subject.ucmGenética médica
dc.subject.ucmMicrobiología médica
dc.subject.unesco2409 Genética
dc.subject.unesco2414 Microbiología
dc.titleAssociations between vitamin D receptor (VDR) polymorphisms and gut microbiota in a spanish population sample
dc.typeconference paper
dc.type.hasVersionVoR
dspace.entity.typePublication
relation.isAuthorOfPublicationebff6da2-2b42-406f-95ca-3b41ec966aa3
relation.isAuthorOfPublication.latestForDiscoveryebff6da2-2b42-406f-95ca-3b41ec966aa3

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