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No association between the Ser9Gly polymorphism of the dopamine D3 receptor gene and schizophrenia in a Spanish sample.

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No association between the Ser9Gly polymorphism of the dopamine D3 American J of Med Genetics Pt B - 2006 - Lorenzo -.pdf (53.41 KB)

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https://onlinelibrary.wiley.com/doi/10.1002/ajmg.b.30331

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2006

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Wiley
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https://hdl.handle.net/20.500.14352/95598

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Lorenzo CV, Baca-Garcia E, Hernandez MD, Martin CB, Perez-Rodriguez MM, Saiz-Gonzalez MD, Fernández P, Gutierrez FJ, Saiz-Ruiz J, Piqueras JF, de Rivera JL, de Leon J. No association between the Ser9Gly polymorphism of the dopamine D3 receptor gene and schizophrenia in a Spanish sample. Am J Med Genet B Neuropsychiatr Genet. 2007 Apr 5;144B(3):344-6. doi: 10.1002/ajmg.b.30331. PMID: 17171662.

Abstract

This study aims to further evaluate the controversial association between the Ser9Gly polymorphism in codon 9 of the D3 dopamine receptor gene (DRD3) and schizophrenia in psychiatric inpatients acutely hospitalized in two general hospitals in Madrid, Spain. The Ser9Gly polymorphism of the DRD3 was examined in 178 schizophrenic patients, 286 patients with other psychiatric diagnoses, and 132 controls recruited. Genotype frequencies were in Hardy-Weinberg equilibrium. No association was found between schizophrenia and the Ser9Gly polymorphism of the D3 dopamine receptor gene

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