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Influence of Contact Lens Parameters on Cornea: Biomechanical Analysis

dc.contributor.authorRamasubramanian, Darshan
dc.contributor.authorHernández Verdejo, José Luis
dc.contributor.authorLópez Alonso, José Manuel
dc.date.accessioned2024-11-28T13:51:57Z
dc.date.available2024-11-28T13:51:57Z
dc.date.issued2024-09
dc.description.abstractThis study presents a finite element analysis to model ocular biomechanics and the interactions between the human eye and contact lenses in the closed-eye condition. The closed-eye state, where the eyelids are fully shut, presents challenges for experimental measurements due to the invasive nature of accessing and analysing the contact lens and corneal interface, making simulation tools valuable for accurate characterisation. The primary objective of this study was to examine how CLs fold and twist and their impact on the cornea when the eye is closed. The secondary aim of this study was to assess how crucial contact lens parameters (Young’s modulus, base curve, and diameter) influence corneal stress distribution and the overall fit of the lens on the eye. The findings show that increasing Young’s modulus significantly reduces corneal stress and promotes uniform stress distribution, making it the most influential factor for wearer comfort and safety. While base curve and diameter variations primarily affect contact area, their impact on stress distribution is minimal. This research provides insights for improving contact lens design and enhancing safety for contact lens wearers.
dc.description.departmentDepto. de Optometría y Visión
dc.description.facultyFac. de Óptica y Optometría
dc.description.refereedTRUE
dc.description.sponsorshipMarie Skłodowska-Curie Grant
dc.description.statuspub
dc.identifier.citationRamasubramanian, D.; Hernández-Verdejo, J.L.; López-Alonso, J.M. Influence of Contact Lens Parameters on Cornea: Biomechanical Analysis. Bioengineering 2024, 11, 966. https://doi.org/10.3390/bioengineering11100966
dc.identifier.doi10.3390/bioengineering11100966
dc.identifier.officialurlhttps://doi.org/10.3390/bioengineering11100966
dc.identifier.urihttps://hdl.handle.net/20.500.14352/111202
dc.journal.titleBioengineering
dc.language.isoeng
dc.publisherMDPI
dc.relation.projectIDinfo:eu-repo/grantAgreement/EC/H2020/956274
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internationalen
dc.rights.accessRightsopen access
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject.cdu611.841.2
dc.subject.cdu617.7-089.243
dc.subject.keywordFinite element analysis
dc.subject.keywordOcular biomechanics
dc.subject.keywordContact lens design
dc.subject.keywordWearer comfort
dc.subject.ucmÓptica y optometría
dc.subject.unesco2209.15 Optometría
dc.titleInfluence of Contact Lens Parameters on Cornea: Biomechanical Analysis
dc.typejournal article
dc.type.hasVersionVoR
dspace.entity.typePublication
relation.isAuthorOfPublication2ed110d3-f335-4688-9c14-1a56e56e8d28
relation.isAuthorOfPublicatione52aef01-c246-4f9f-9cfd-d9dfb2a8ee79
relation.isAuthorOfPublication.latestForDiscovery2ed110d3-f335-4688-9c14-1a56e56e8d28

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