Publication:
Differences in the Outcome of Patients with COPD according to Body Mass Index

dc.contributor.authorJi, Zichen
dc.contributor.authorde Miguel-Díez, Javier
dc.contributor.authorCastro-Riera, Christian Reynaldo
dc.contributor.authorBellón-Cano, José María
dc.contributor.authorGallo-González, Virginia
dc.contributor.authorGirón-Matute, Walther Iván
dc.contributor.authorJiménez García, Rodrigo
dc.contributor.authorLópez-de Andrés, Ana
dc.contributor.authorMoya-Álvarez, Virginia
dc.contributor.authorPuente-Maestu, Luis
dc.contributor.authorHernández-Vázquez, Julio
dc.date.accessioned2023-06-17T09:06:54Z
dc.date.available2023-06-17T09:06:54Z
dc.date.issued2020-03-05
dc.description.abstractBackground: In chronic obstructive pulmonary disease (COPD), the “obesity paradox” is a phenomenon without a clear cause. The objective is to analyze the complications of COPD patients according to their body mass index (BMI). Methods: An observational study with a six-year prospective follow-up of 273 COPD patients who attended a spirometry test in 2011. Survival and acute events were analyzed according to the BMI quartiles. Results: A total of 273 patients were included. BMI quartiles were ≤24.23; 24.24–27.69; 27.70–31.25; ≥31.26. During the follow-up, 93 patients died. No differences were found in exacerbations, pneumonia, emergency visits, hospital admissions or income in a critical unit. Survival was lower in the quartile 1 of BMI with respect to each of the 2–4 quartiles (p-value 0.019, 0.013, and 0.004, respectively). Advanced age (hazard ratio, HR 1.06; 95% confidence interval, CI 1.03–1.09), low pulmonary function (HR 0.93; 95% CI 0.86–0.99), exacerbator with chronic bronchitis phenotype (HR 1.76; 95% CI 1.01–3.06), high Charlson (HR 1.32, 95% CI 1.18–1.49), and the quartile 1 of BMI (HR 1.99, 95% CI 1.08–3.69) were identified as risk factors independently associated with mortality. Conclusions: In COPD, low BMI conditions a lower survival, although not for having more acute events.
dc.description.departmentDepto. de Salud Pública y Materno - Infantil
dc.description.facultyFac. de Medicina
dc.description.refereedTRUE
dc.description.statuspub
dc.eprint.idhttps://eprints.ucm.es/id/eprint/65894
dc.identifier.doi10.3390/jcm9030710
dc.identifier.issn2077-0383
dc.identifier.officialurlhttps://doi.org/10.3390/jcm9030710
dc.identifier.relatedurlhttps://www.mdpi.com/2077-0383/9/3/710
dc.identifier.urihttps://hdl.handle.net/20.500.14352/8202
dc.issue.number3
dc.journal.titleJournal of Clinical Medicine
dc.language.isoeng
dc.page.initial710
dc.publisherMDPI
dc.rightsAtribución 3.0 España
dc.rights.accessRightsopen access
dc.rights.urihttps://creativecommons.org/licenses/by/3.0/es/
dc.subject.keywordchronic obstructive pulmonary disease (COPD)
dc.subject.keywordbody mass index
dc.subject.keywordsurvival
dc.subject.keywordrisk factor
dc.subject.ucmDietética y nutrición (Medicina)
dc.subject.unesco3206 Ciencias de la Nutrición
dc.titleDifferences in the Outcome of Patients with COPD according to Body Mass Index
dc.typejournal article
dc.volume.number9
dspace.entity.typePublication
relation.isAuthorOfPublication5db1f21a-0369-4191-96f5-b640ed0f3dde
relation.isAuthorOfPublication.latestForDiscovery5db1f21a-0369-4191-96f5-b640ed0f3dde
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