Molecular organization of small plasmids bearing blaTEM-1 and conferring resistance to β-lactams in Haemophilus influenzae
| dc.contributor.author | Søndergaard, Annette | |
| dc.contributor.author | San Millan, Alvaro | |
| dc.contributor.author | Santos López, Alfonso | |
| dc.contributor.author | Nielsen, Signe M | |
| dc.contributor.author | González Zorn, Bruno | |
| dc.contributor.author | Nørskov-Lauritsen, Niels | |
| dc.date.accessioned | 2023-06-20T04:19:28Z | |
| dc.date.available | 2023-06-20T04:19:28Z | |
| dc.date.issued | 2012-09 | |
| dc.description.abstract | TEM-1 is the dominant β-lactamase of Haemophilus influenzae and can be located on small plasmids. Three distinct plasmids with sizes from 4,304 to 5,646 nucleotides (nt) were characterized: pA1606, pA1209, and pPN223. In addition to TEM-1 and a replication enzyme of the Rep 3 superfamily, pA1606 carries a Tn3 resolvase gene and pA1606 and pA1209 carry an open reading frame (ORF) similar to a plasmid recombination enzyme gene described in Gram-positive bacteria. The plasmids transformed strain Rd to the ampicillin-resistant phenotype. | |
| dc.description.faculty | Centro de Vigilancia Sanitaria Veterinaria (VISAVET) | |
| dc.description.refereed | TRUE | |
| dc.description.status | pub | |
| dc.eprint.id | https://eprints.ucm.es/id/eprint/39668 | |
| dc.identifier.doi | 10.1128/AAC.00408-12 | |
| dc.identifier.issn | 1098-6596 | |
| dc.identifier.officialurl | http://aac.asm.org/content/56/9/4958.full | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14352/45168 | |
| dc.issue.number | 9 | |
| dc.journal.title | Antimicrobial agents and chemotherapy | |
| dc.language.iso | eng | |
| dc.page.final | 60 | |
| dc.page.initial | 4958 | |
| dc.publisher | American Society for Microbiology | |
| dc.rights.accessRights | restricted access | |
| dc.subject.ucm | Veterinaria | |
| dc.subject.unesco | 3109 Ciencias Veterinarias | |
| dc.title | Molecular organization of small plasmids bearing blaTEM-1 and conferring resistance to β-lactams in Haemophilus influenzae | |
| dc.type | journal article | |
| dc.volume.number | 56 | |
| dspace.entity.type | Publication | |
| relation.isAuthorOfPublication | abbfe61a-3e58-4cfb-85fc-d2e2ec46b0a3 | |
| relation.isAuthorOfPublication.latestForDiscovery | abbfe61a-3e58-4cfb-85fc-d2e2ec46b0a3 |
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