Non-Invasive Breast Cancer Diagnosis through Electrochemical Biosensing at Different Molecular Levels

Simple item page
dc.contributor.authorCampuzano, Susana
dc.contributor.authorPedrero Muñoz, María
dc.contributor.authorPingarrón Carrazón, José Manuel
dc.date.accessioned2023-06-17T22:07:20Z
dc.date.available2023-06-17T22:07:20Z
dc.date.issued2017-09
dc.description.abstractThe rapid and accurate determination of specific circulating biomarkers at different molecular levels with non- or minimally invasive methods constitutes a major challenge to improve the breast cancer outcomes and life quality of patients. In this field, electrochemical biosensors have demonstrated to be promising alternatives against more complex conventional strategies to perform fast, accurate and on-site determination of circulating biomarkers at low concentrations in minimally treated body fluids. In this article, after discussing briefly the relevance and current challenges associated with the determination of breast cancer circulating biomarkers, an updated overview of the electrochemical affinity biosensing strategies emerged in the last 5 years for this purpose is provided highlighting the great potentiality of these methodologies. After critically discussing the most interesting features of the electrochemical strategies reported so far for the single or multiplexed determination of such biomarkers with demonstrated applicability in liquid biopsy analysis, existing challenges still to be addressed and future directions in this field will be pointed out.
dc.description.departmentDepto. de Química Analítica
dc.description.facultyFac. de Ciencias Químicas
dc.description.refereedTRUE
dc.description.sponsorshipMinisterio de Economía y Competitividad (MINECO)
dc.description.sponsorshipComunidad de Madrid
dc.description.statuspub
dc.eprint.idhttps://eprints.ucm.es/id/eprint/44736
dc.identifier.doi10.3390/s17091993
dc.identifier.issn1424-8220
dc.identifier.officialurlhttps://doi.org/10.3390/s17091993
dc.identifier.relatedurlhttp://www.mdpi.com/1424-8220/17/9/1993/htm
dc.identifier.urihttps://hdl.handle.net/20.500.14352/18095
dc.issue.number9
dc.journal.titleSensors
dc.language.isoeng
dc.publisherMDPI
dc.relation.projectIDCTQ2015-64402-C2-1-R
dc.relation.projectIDNANOAVANSENS (S2013/MT-3029)
dc.rightsAtribución 3.0 España
dc.rights.accessRightsopen access
dc.rights.urihttps://creativecommons.org/licenses/by/3.0/es/
dc.subject.cdu543
dc.subject.keywordbreast cancer
dc.subject.keywordcirculating biomarkers
dc.subject.keywordnanomaterials
dc.subject.keywordelectrochemical affinity biosensors
dc.subject.ucmQuímica analítica (Química)
dc.subject.unesco2301 Química Analítica
dc.titleNon-Invasive Breast Cancer Diagnosis through Electrochemical Biosensing at Different Molecular Levels
dc.typejournal article
dc.volume.number17
dspace.entity.typePublication
relation.isAuthorOfPublication422f8844-54d1-4615-98e8-ef5a0c7e3519
relation.isAuthorOfPublication8808f99c-5f56-4562-839a-517626c76dad
relation.isAuthorOfPublication.latestForDiscovery422f8844-54d1-4615-98e8-ef5a0c7e3519
Download
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Review BC-SI Sensors.pdf
Size:
4.52 MB
Format:
Adobe Portable Document Format
downoload Download
Collections
Artículos