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Tefluthrin: metabolism, food residues, toxicity, and mechanisms of action

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dc.contributor.authorWang, Xiaohui
dc.contributor.authorLi, Houpeng
dc.contributor.authorWang, Simeng
dc.contributor.authorMartínez Caballero, María Aranzazu
dc.contributor.authorMartínez Caballero, Marta
dc.contributor.authorAres Lombán, Irma
dc.contributor.authorMartínez Larrañaga, María Rosa
dc.contributor.authorWang, Xu
dc.contributor.authorAnadón Navarro, Arturo Ramón
dc.contributor.authorMaximiliano Guerra, Jorge Enrique
dc.date.accessioned2025-10-13T18:15:43Z
dc.date.available2025-10-13T18:15:43Z
dc.date.issued2023
dc.description.abstractTefluthrin is a Type I pyrethroid insecticide widely used all over the world. Residues of tefluthrin in various agricultural and animal-derived products may be related to potential human health risks. Tefluthrin metabolism in mammals involves hydrolysis of the ester bond to form cyclopropane acid and 4-methylbenzyl alcohol moieties, followed by oxidation. In this review manuscript, we provide crucial information regarding the toxicity of pyrethroids and propose natural antioxidants for amelioration poisoning in humans and animals. We call for the rational use of tefluthrin as an agrochemical product and for greater attention to the residual toxicity caused by tefluthrin in primary and succeeding crops. This greater attention is required given the global use of tefluthrin.
dc.description.departmentDepto. de Farmacología y Toxicología
dc.description.facultyFac. de Veterinaria
dc.description.refereedTRUE
dc.description.sponsorshipMinisterio de Ciencia e Innovación (España)
dc.description.statuspub
dc.identifier.citationWang, X., Li, H., Wang, S., Martínez, M.-A., Ares, I., Martínez, M., Martínez-Larrañaga, M.-R., Wang, X., Anadón, A., & Maximiliano, J.-E. (2022). [Rev. of Tefluthrin: metabolism, food residues, toxicity, and mechanisms of action]. Critical Reviews in Toxicology, 52(8), 664-680. https://doi.org/10.1080/10408444.2022.2143320
dc.identifier.doihttps://doi.org/10.1080/10408444.2022.2143320
dc.identifier.essn1547-6898
dc.identifier.isbn1040-8444
dc.identifier.officialurlhttps://doi.org/10.1080/10408444.2022.2143320
dc.identifier.pmid36625435
dc.identifier.urihttps://hdl.handle.net/20.500.14352/124851
dc.issue.number8
dc.journal.titleCritical Reviews in Toxicology
dc.language.isoeng
dc.page.final680
dc.page.initial664
dc.publisherTaylor & Francis
dc.relation.projectIDPID2020-115979RR-C33
dc.relation.projectID2662020DKPY020
dc.rights.accessRightsrestricted access
dc.subject.cdu615.9
dc.subject.keywordTefluthrin
dc.subject.keywordFood residues
dc.subject.keywordMechanism
dc.subject.keywordOxidative stress
dc.subject.keywordToxicity
dc.subject.ucmCiencias Biomédicas
dc.subject.unesco3214 Toxicología
dc.titleTefluthrin: metabolism, food residues, toxicity, and mechanisms of action
dc.typejournal article
dc.type.hasVersionVoR
dc.volume.number52
dspace.entity.typePublication
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relation.isAuthorOfPublication.latestForDiscovery72e3a3ef-d7b1-4c63-9ea3-d0d3d543514f

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