Morphometry of the trabecular meshwork in vivo in a healthy population using fourier-domain optical coherence tomography

dc.contributor.authorFernández Vigo, José Ignacio
dc.contributor.authorGarcía Feijoo, Julián
dc.contributor.authorMartínez De La Casa Fernández-Borrella, José María
dc.contributor.authorGarcía Bella, Javier
dc.contributor.authorFernández Vigo, José Ángel
dc.dateSubmitted: November 27, 2014 / Accepted: February 11, 2015
dc.date.accessioned2023-06-18T05:42:07Z
dc.date.available2023-06-18T05:42:07Z
dc.date.issued2015-03
dc.descriptionEn abierto en la web del editor.
dc.description.abstractPURPOSE. We measured the length, thickness, and area of the trabecular meshwork (TM) in vivo using Fourier domain optical coherence tomography (FD-OCT) in a Caucasian population of healthy subjects. METHODS. A cross-sectional study was done of 1006 healthy subjects. Left eyes were randomly selected. Age, sex, IOP, and spherical refractive error were noted. The depth and volume of the anterior chamber and the central corneal thickness were measured with Pentacam, while IOL Master was used to measure the axial length. The length, thickness, and area of the TM were measured through FD-OCT RTVue. A study was done to determine the correlation between TM size, and other demographic and ocular parameters. Finally, the reproducibility of the measurements was assessed for a subgroup of 50 eyes from 50 patients. RESULTS. We were able to measure the TM in 91.1% of the total eyes studied. The mean TM length was 496.99 6 92.77 lm (range, 275–800), TM thickness was 174.16 6 28.14 lm (range, 100–276), and TM area was 0.069 6 0.031 mm2 (range, 0.023–0.133). No differences were found in terms of length and area for sex, although the TM was slightly thicker in men (P ¼ 0.046). No correlation was observed between the TM measurements and any of the studied demographic or ocular parameters (R < 0.09, P < 0.001). Intra- and interobserver reproducibility of the measurements were good (intraclass correlation coefficient > 0.750, P < 0.001). CONCLUSIONS. The FD-OCT is an effective and reproducible examination technique to measure the length, thickness, and area of the TM in vivo.en
dc.description.departmentUnidad Docente de Inmunología, Oftalmología y ORL
dc.description.facultyFac. de Óptica y Optometría
dc.description.refereedTRUE
dc.description.statuspub
dc.eprint.idhttps://eprints.ucm.es/id/eprint/40999
dc.identifier.citationFernandez Vigo, J. I., García Feijoo, J., Martínez De La Casa Fernández-Borrella, J. M. et al. «Morphometry of the Trabecular Meshwork In Vivo in a Healthy Population Using Fourier-Domain Optical Coherence Tomography». Investigative Ophthalmology & Visual Science, vol. 56, n.o 3, marzo de 2015, pp. 1782-88. DOI.org (Crossref), https://doi.org/10.1167/iovs.14-16154.
dc.identifier.doi10.1167/iovs.14-16154
dc.identifier.essn1552-5783
dc.identifier.issn0146-0404
dc.identifier.officialurlhttp://doi.org/10.1167/iovs.14-16154
dc.identifier.urihttps://hdl.handle.net/20.500.14352/23094
dc.issue.number3
dc.journal.titleInvestigative Ophthalmology & Visual Science
dc.language.isoeng
dc.page.final1788
dc.page.initial1782
dc.publisherThe Association for Research in Vision and Ophthalmology, Inc.
dc.rightsAtribución-NoComercial-SinDerivadas 3.0 España
dc.rights.accessRightsopen access
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/3.0/es/
dc.subject.cdu617.7-073.75
dc.subject.cdu535.4
dc.subject.keywordTrabecular meshwork
dc.subject.keywordOptical coherence tomography
dc.subject.keywordGlaucoma anterior segment
dc.subject.ucmOftalmología
dc.subject.ucmÓptica geométrica e instrumental
dc.subject.ucmTécnicas de la imagen
dc.subject.unesco3201.09 Oftalmología
dc.subject.unesco2209.06 Óptica geométrica
dc.titleMorphometry of the trabecular meshwork in vivo in a healthy population using fourier-domain optical coherence tomographyen
dc.typejournal article
dc.volume.number56
dspace.entity.typePublication
relation.isAuthorOfPublication558b8023-6d72-4dff-9f99-2e60f6f31843
relation.isAuthorOfPublication273a99c3-2c9f-4dd0-8939-b7ff3593124c
relation.isAuthorOfPublication.latestForDiscovery558b8023-6d72-4dff-9f99-2e60f6f31843
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