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Genetic regulation of aflatoxin, ochratoxin A, trichothecene, and fumonisin biosynthesis: A review

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dc.contributor.authorGil Serna, Jessica
dc.contributor.authorVázquez Estévez, María Covadonga Inmaculada
dc.contributor.authorPatiño Álvarez, Aurora Belén
dc.date.accessioned2023-06-17T12:30:24Z
dc.date.available2023-06-17T12:30:24Z
dc.date.issued2019-05-29
dc.description.abstractMycotoxins are a significant food safety concern. Aflatoxins, trichothecenes, fumonisins, and ochratoxin A are considered the most important mycotoxins due to their frequent occurrence in food products and their well-known toxicity. The regulation of mycotoxin biosynthesis occurs mainly at transcriptional level, and specific regulators have been described in every biosynthetic cluster. Secondary metabolite production, including mycotoxin synthesis, is also regulated by general regulator pathways affected by light, osmotic stress and oxidative stress, among others. This review is focused on this genetic regulation of mycotoxin biosynthesis by specific genes and global regulators.
dc.description.departmentDepto. de Genética, Fisiología y Microbiología
dc.description.facultyFac. de Ciencias Biológicas
dc.description.refereedTRUE
dc.description.sponsorshipMinisterio de Ciencia e Innovación (MICINN)
dc.description.statuspub
dc.eprint.idhttps://eprints.ucm.es/id/eprint/60554
dc.identifier.doi10.1007/s10123-019-00084-2
dc.identifier.issn1618-1905
dc.identifier.officialurlhttps://link-springer-com.bucm.idm.oclc.org/article/10.1007/s10123-019-00084-2
dc.identifier.urihttps://hdl.handle.net/20.500.14352/12326
dc.journal.titleInternational Microbiology
dc.language.isoeng
dc.page.final96
dc.page.initial89
dc.publisherSpringer
dc.relation.projectID(AGL 2014-53928-C2-2-R)
dc.rightsAtribución-NoComercial-CompartirIgual 3.0 España
dc.rights.accessRightsopen access
dc.rights.urihttps://creativecommons.org/licenses/by-nc-sa/3.0/es/
dc.subject.cdu577.1
dc.subject.cdu575
dc.subject.keywordAflatoxins
dc.subject.keywordTrichothecenes
dc.subject.keywordFumonisin
dc.subject.keywordOchratoxin A
dc.subject.keywordBiosynthetic cluster
dc.subject.keywordTranscription factors
dc.subject.ucmBioquímica (Biología)
dc.subject.ucmGenética
dc.subject.unesco2302 Bioquímica
dc.subject.unesco2409 Genética
dc.titleGenetic regulation of aflatoxin, ochratoxin A, trichothecene, and fumonisin biosynthesis: A review
dc.typejournal article
dc.volume.number23
dspace.entity.typePublication
relation.isAuthorOfPublication413efe47-272c-4f1a-aae9-722b00567716
relation.isAuthorOfPublicationf4a0f192-eb84-459c-8126-d38dfdca1724
relation.isAuthorOfPublicationb71ac7e7-f329-4d04-b48d-8b518b822d0b
relation.isAuthorOfPublication.latestForDiscoveryf4a0f192-eb84-459c-8126-d38dfdca1724

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