First characterization of fluoroquinolone resistance in Streptococcus suis

San Millán, Álvaro; Catalán, Ana; González de la Campa, Adela; Rivero, Estefanía; Lopez, Gema; Escudero García-Calderón, José Antonio; Domínguez Rodríguez, Lucas José; Moreno Romo, Miguel Ángel; González Zorn, Bruno

First characterization of fluoroquinolone resistance in Streptococcus suis

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Official URL

https://journals.asm.org/doi/10.1128/aac.00972-06

Publication date

2007

Authors

San Millán, Álvaro

Catalán, Ana

González de la Campa, Adela

Rivero, Estefanía

Lopez, Gema

Escudero García-Calderón, José Antonio

Domínguez Rodríguez, Lucas José

Moreno Romo, Miguel Ángel

González Zorn, Bruno

Publisher

American Society for Microbiology

Citations

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URI

https://hdl.handle.net/20.500.14352/94239

Citation

Escudero, J. A., San Millan, A., Catalan, A., de la Campa, A. G., Rivero, E., Lopez, G., Dominguez, L., Moreno, M. A., & Gonzalez-Zorn, B. (2007). First characterization of fluoroquinolone resistance in Streptococcus suis. Antimicrobial agents and chemotherapy, 51(2), 777–782. https://doi.org/10.1128/AAC.00972-06

Abstract

We have identified and sequenced the genes encoding the quinolone-resistance determining region (QRDR) of ParC and GyrA in fluoroquinolone-susceptible and -resistant Streptococcus suis clinical isolates. Resistance is the consequence of single point mutations in the QRDRs of ParC and GyrA and is not due to clonal spread of resistant strains or horizontal gene transfer with other bacteria.