High Vancomycin MIC and Complicated Methicillin-Susceptible Staphylococcus aureus Bacteremia
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2011
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Centers for Disease Control and Prevention
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Aguado JM, San-Juan R, Lalueza A, Sanz F, Rodríguez-Otero J, Gómez-Gonzalez C, Chaves F. High vancomycin MIC and complicated methicillin-susceptible Staphylococcus aureus bacteremia. Emerg Infect Dis. 2011 Jun;17(6):1099-102. doi: 10.3201/eid/1706.101037. PMID: 21749780; PMCID: PMC3358192.
Abstract
We conducted a retrospective study of 99 patients with methicillin-suseptible Staphylococcus aureus catheter-related bacteremia in which vancomycin MIC was determined by Etest. High vancomycin MIC (>1.5 μg/mL) was the only independent risk factor for development of complicated bacteremia caused by methicillin-susceptible S. aureus (odds ratio 22.9, 95% confidence interval 6.7–78.1).