Streptococcus pneumoniae Isolates with Reduced Susceptibility to Ciprofloxacin in Spain: Clonal Diversity and Appearance of Ciprofloxacin-Resistant Epidemic Clones

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dc.contributor.authorAlou Cervera, Luis
dc.contributor.authorRamirez, Mario
dc.contributor.authorGarcı́a-Rey, César
dc.contributor.authorPrieto Prieto, José
dc.contributor.authorde Lencastre, Hermı́nia
dc.date.accessioned2024-07-23T12:08:19Z
dc.date.available2024-07-23T12:08:19Z
dc.date.issued2001-10
dc.description.abstractABSTRACT Analysis of the pulsed-field gel electrophoretic profiles of 82 pneumococcal isolates with reduced susceptibility to ciprofloxacin (RSC) and of 90 co-occurring susceptible isolates indicates a considerable genetic diversity among isolates with RCS and points to a close relation between the two groups. This finding suggests that pneumococci with RCS emerge through independent mutational events.
dc.description.departmentDepto. de Medicina
dc.description.facultyFac. de Medicina
dc.description.refereedTRUE
dc.description.sponsorshipJunta Nacional de Investigação Cientı́fica e Tecnológica (Portugal)
dc.description.statuspub
dc.identifier.citationAlou L, Ramirez M, García-Rey C, Prieto J, de Lencastre H. Streptococcus pneumoniae isolates with reduced susceptibility to ciprofloxacin in Spain: clonal diversity and appearance of ciprofloxacin-resistant epidemic clones. Antimicrob Agents Chemother. 2001 Oct;45(10):2955-7. doi: 10.1128/AAC.45.10.2955-2957.2001
dc.identifier.doi10.1128/aac.45.10.2955-2957.2001
dc.identifier.issn0066-4804
dc.identifier.issn1098-6596
dc.identifier.officialurlhttps://doi.org/10.1128/aac.45.10.2955-2957.2001
dc.identifier.relatedurlhttps://journals.asm.org/doi/10.1128/aac.45.12.3678-3678.2001
dc.identifier.urihttps://hdl.handle.net/20.500.14352/107054
dc.issue.number10
dc.journal.titleAntimicrobial Agents and Chemotherapy
dc.language.isoeng
dc.page.final2957
dc.page.initial2955
dc.publisherAmerican Society for Microbiology
dc.relation.projectIDPRAXIS/P/SAU14051/1998
dc.rights.accessRightsrestricted access
dc.subject.cdu611.02
dc.subject.ucmMicrobiología médica
dc.subject.unesco2414 Microbiología
dc.titleStreptococcus pneumoniae Isolates with Reduced Susceptibility to Ciprofloxacin in Spain: Clonal Diversity and Appearance of Ciprofloxacin-Resistant Epidemic Clones
dc.typejournal article
dc.type.hasVersionAM
dc.volume.number45
dspace.entity.typePublication
relation.isAuthorOfPublication889e4dc3-c630-429e-be0f-7f0df2cff492
relation.isAuthorOfPublication84cd82de-c5ea-4fed-a347-4ed15fb3bcc8
relation.isAuthorOfPublication.latestForDiscovery889e4dc3-c630-429e-be0f-7f0df2cff492

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