In vitro activity of mupirocin and amoxicillin-clavulanate alone and in combination against staphylococci including those resistant to methicillin
| dc.contributor.author | Alou Cervera, Luis | |
| dc.contributor.author | Cafini, Fabio | |
| dc.contributor.author | Sevillano Fernández, David | |
| dc.contributor.author | Unzueta, Irune | |
| dc.contributor.author | Prieto Prieto, José | |
| dc.date.accessioned | 2024-07-23T12:14:49Z | |
| dc.date.available | 2024-07-23T12:14:49Z | |
| dc.date.issued | 2004-05 | |
| dc.description.abstract | Mupirocin and amoxicillin-clavulanate were synergistic against 9 of 49 (18%) strains of methicillin-resistant and methicillin-susceptible Staphylococcus aureus and coagulase-negative staphylococci (CNS). A pattern of enhanced killing was also found using time-kill studies. Time-kill assays were more discriminatory than chequerboard titration assays in demonstrating synergy. These results suggest that combinations of amoxicillin-clavulanate and mupirocin may have therapeutic benefits in prophylaxis against staphylococcal infections. | |
| dc.description.department | Depto. de Medicina | |
| dc.description.faculty | Fac. de Medicina | |
| dc.description.refereed | TRUE | |
| dc.description.status | pub | |
| dc.identifier.citation | Alou L, Cafini F, Sevillano D, Unzueta I, Prieto J. In vitro activity of mupirocin and amoxicillin-clavulanate alone and in combination against staphylococci including those resistant to methicillin. Int J Antimicrob Agents. 2004 May;23(5):513-6. | |
| dc.identifier.doi | 10.1016/j.ijantimicag.2003.09.030 | |
| dc.identifier.issn | 0924-8579 | |
| dc.identifier.officialurl | https://doi.org/10.1016/j.ijantimicag.2003.09.030 | |
| dc.identifier.relatedurl | https://www.sciencedirect.com/science/article/pii/S0924857904000482 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14352/107056 | |
| dc.issue.number | 5 | |
| dc.journal.title | International Journal of Antimicrobial Agents | |
| dc.language.iso | eng | |
| dc.page.final | 516 | |
| dc.page.initial | 513 | |
| dc.publisher | Elsevier | |
| dc.rights.accessRights | restricted access | |
| dc.subject.cdu | 611.02 | |
| dc.subject.keyword | Prophylaxis | |
| dc.subject.keyword | Catheters | |
| dc.subject.keyword | Vascular-graft infection | |
| dc.subject.ucm | Microbiología médica | |
| dc.subject.unesco | 2414 Microbiología | |
| dc.title | In vitro activity of mupirocin and amoxicillin-clavulanate alone and in combination against staphylococci including those resistant to methicillin | |
| dc.type | journal article | |
| dc.type.hasVersion | VoR | |
| dc.volume.number | 23 | |
| dspace.entity.type | Publication | |
| relation.isAuthorOfPublication | 889e4dc3-c630-429e-be0f-7f0df2cff492 | |
| relation.isAuthorOfPublication | 518c916a-df78-48cc-9bf7-6a2aaca7d6a2 | |
| relation.isAuthorOfPublication | 84cd82de-c5ea-4fed-a347-4ed15fb3bcc8 | |
| relation.isAuthorOfPublication.latestForDiscovery | 889e4dc3-c630-429e-be0f-7f0df2cff492 |
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