Publication:
Dietary Intake of Cadmium, Lead and Mercury and Its Association with Bone Health in Healthy Premenopausal Women

dc.contributor.authorLavado-García, Jesus
dc.contributor.authorPuerto-Parejo, Luis
dc.contributor.authorRoncero-Martín, Raul
dc.contributor.authorMoran, Jose
dc.contributor.authorPedrera-Zamorano, Juan
dc.contributor.authorAliaga Vera, Ignacio
dc.contributor.authorLeal-Hernández, Olga
dc.contributor.authorCanal-Macias, Maria
dc.date.accessioned2023-06-17T23:58:15Z
dc.date.available2023-06-17T23:58:15Z
dc.date.issued2017
dc.description.abstractThe bone is one of the relevant target organs of heavy metals, and heavy metal toxicity is associated with several degenerative processes, such osteoporosis and bone mineral alterations, that could lead to fractures. We aimed to study a presumed relationship between bone density, evaluated by quantitative bone ultrasound (QUS), dual-energy X-ray absorptiometry (DXA) and peripheral quantitative computed tomography (pQCT) and the dietary intake of cadmium, lead and mercury in healthy premenopausal women. A total of 158 healthy, non-smoking, premenopausal women were incorporated into the study. A validated food frequency questionnaire (FFQ) was administered to assess intake during the preceding seven days. The median predicted dietary cadmium intake among the 158 women studied was 25.29 µg/day (18.62–35.00) and 2.74 µg/kg body weight/week (b.w./w) (1.92–3.83). Dietary lead intake was 43.85 µg/day (35.09–51.45) and 4.82 µg/kg b.w./w (3.67–6.13). The observed dietary mercury intake was 9.55 µg/day (7.18–13.57) and 1.02 µg/kg b.w./w (0.71–1.48). Comparisons, in terms of heavy metal intake, showed no significant results after further adjusting for energy intake. No statistically significant correlations between heavy metal intake and the QUS, DXA and pQCT parameters were observed. Levels of dietary exposure of cadmium, lead and mercury were mostly within the recommendations. We did not find associations between the QUS, DXA and pQCT parameters and the dietary intake of the studied heavy metals in healthy premenopausal women.
dc.description.departmentDepto. de Odontología Conservadora y Prótesis
dc.description.facultyFac. de Odontología
dc.description.refereedTRUE
dc.description.sponsorshipJunta de Extremadura
dc.description.statuspub
dc.eprint.idhttps://eprints.ucm.es/id/eprint/62441
dc.identifier.doi10.3390/ijerph14121437
dc.identifier.issn1660-4601
dc.identifier.officialurlhttps://doi.org/10.3390/ijerph14121437
dc.identifier.relatedurlhttps://www.mdpi.com/1660-4601/14/12/1437
dc.identifier.urihttps://hdl.handle.net/20.500.14352/19101
dc.issue.number12
dc.journal.titleInternational Journal of Environmental Research and Public Health
dc.language.isoeng
dc.page.initial1437
dc.publisherMDPI
dc.relation.projectIDGR15144
dc.rightsAtribución 3.0 España
dc.rights.accessRightsopen access
dc.rights.urihttps://creativecommons.org/licenses/by/3.0/es/
dc.subject.keywordHeavy metals
dc.subject.keywordfood
dc.subject.keyworddietary intake
dc.subject.keywordbone health
dc.subject.keywordwomen’s health
dc.subject.keywordpremenopause
dc.subject.keywordbone mineral density
dc.subject.ucmDietética y nutrición (Medicina)
dc.subject.ucmSistema musculoesquelético
dc.subject.unesco3206 Ciencias de la Nutrición
dc.subject.unesco2411.10 Fisiología del Músculo
dc.titleDietary Intake of Cadmium, Lead and Mercury and Its Association with Bone Health in Healthy Premenopausal Women
dc.typejournal article
dc.volume.number14
dspace.entity.typePublication
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