Lymphoma lurks within aged B cells
dc.contributor.author | Jiménez-Martínez, V. | |
dc.contributor.author | Martín-Subero, José I. | |
dc.contributor.author | Fernández Pérez, Raúl | |
dc.date.accessioned | 2024-12-12T18:16:57Z | |
dc.date.available | 2024-12-12T18:16:57Z | |
dc.date.issued | 2024 | |
dc.description.abstract | Cancer and aging are inextricably linked conditions. However, whether cancer emerges as a byproduct of the aging process or whether aged cells themselves are prone to become neoplastic remains enigmatic. A study by Castro, Shindyapina and colleagues now provides support for the latter by demonstrating that in aged mice that spontaneously develop lymphomas, tumors originate from clonally expanded age-associated B cells. | |
dc.description.department | Depto. de Bioquímica y Biología Molecular | |
dc.description.faculty | Fac. de Veterinaria | |
dc.description.sponsorship | European Commission | |
dc.description.sponsorship | Generalitat de Catalunya | |
dc.description.sponsorship | Ministerio de Ciencia e Innovación (España) | |
dc.description.sponsorship | Fundación Asociación Española Contra el Cáncer | |
dc.description.sponsorship | Ministerio de Ciencia, Innovación y Universidades (España) | |
dc.description.status | pub | |
dc.identifier.doi | 10.1038/s43587-024-00714-z | |
dc.identifier.essn | 2662-8465 | |
dc.identifier.officialurl | https://doi.org/10.1038/s43587-024-00714-z | |
dc.identifier.pmid | 39349623 | |
dc.identifier.relatedurl | https://pubmed.ncbi.nlm.nih.gov/39349623/ | |
dc.identifier.uri | https://hdl.handle.net/20.500.14352/112570 | |
dc.language.iso | eng | |
dc.relation.projectID | info:eu-repo/grantAgreement/EC/H2020/810287/EU | |
dc.relation.projectID | 2021-SGR-01343 | |
dc.relation.projectID | info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PID2020-118167RB-I00/ES/CAUSAS Y CONSECUENCIAS DE LA ACTIVACION DE LA CROMATINA EN EL LINFOMA DE LAS CELULAS DEL MANTO: UN ESTUDIO MECANISTICO Y DE SINGLE CELLS/ | |
dc.relation.projectID | PRYGN234766MART | |
dc.relation.projectID | FPU22/00157 | |
dc.rights.accessRights | restricted access | |
dc.subject.cdu | 577.2 | |
dc.subject.ucm | Biología molecular (Biología) | |
dc.subject.unesco | 2415 Biología Molecular | |
dc.title | Lymphoma lurks within aged B cells | |
dc.type | journal article | |
dc.type.hasVersion | VoR | |
dspace.entity.type | Publication | |
relation.isAuthorOfPublication | 2cdcd922-9fa8-4849-984d-a9fa43f62c5f | |
relation.isAuthorOfPublication.latestForDiscovery | 2cdcd922-9fa8-4849-984d-a9fa43f62c5f |
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