Monomeric ATP Synthases
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2023
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Wiley-VCH GmbH
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Valdivieso González, D., Makowski, M., Lillo, M.P., Cao-García, F.J., Melo, M.N., Almendro-Vedia, V.G. and López-Montero, I. (2023), Rotation of the c-Ring Promotes the Curvature Sorting of Monomeric ATP Synthases (Adv. Sci. 31/2023). Adv. Sci., 10: 2370213. https://doi.org/10.1002/advs.202370213
Abstract
Monomeric ATP synthases exhibit a preference for curved lipid filaments. The curvatureseeking behavior relies on the membrane-mediated attractive interaction between rotating ATP synthases. As a result, conic-like transient dimers produce a dynamic coupling between protein shape and membrane curvature. The observed active curvature sorting suggests a new role for the rotational movement ATP synthases and their dynamic self-assembly. More details can be found in article number 2301606 by Víctor G. Almendro-Vedia, Iván López-Montero, and co-workers.