An Easily Built Smoking Machine for Use by Undergraduate Students in the Determination of Total Particulate Matter and Nicotine in Tobacco Smoke

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dc.contributor.authorGonzález Ruiz, Víctor
dc.contributor.authorMartín Carmona, María Antonia
dc.contributor.authorOlives Barba, Ana Isabel
dc.date.accessioned2024-02-07T08:51:36Z
dc.date.available2024-02-07T08:51:36Z
dc.date.issued2012-04-11
dc.description.abstractSampling mainstream cigarette smoke is a challenging and stimulating laboratory activity for undergraduate students. In addition to the public health significance, cigarette smoke is an unusual source of analytes to examine the differences between gaseous matrices versus liquid or solid matrices. Sophisticated automated smoking machines complying with international standards are not affordable for educational purposes. However, a less expensive and simple smoking apparatus can be easily built in any laboratory that yields reproducible smoking conditions and allows several cigarettes to be smoked simultaneously. We describe the construction of such an apparatus utilizing a solid-phase extraction manifold and chamber, and how it can be used by undergraduate students to generate cigarette smoke and trap the total particulate matter (TPM). The TPM can be later gravimetrically quantified and eluted with 2-propanol containing an internal standard to quantify th nicotine content. Because a set of six cigarettes can be “smoked” simultaneously, the proposed procedure allows the comparison of TPM and nicotine content in mainstream smoke from normal and light cigarettes
dc.description.departmentDepto. de Química en Ciencias Farmacéuticas
dc.description.facultyFac. de Farmacia
dc.description.refereedTRUE
dc.description.sponsorshipUniversidad Complutense de Madrid
dc.description.statuspub
dc.identifier.citationGonzález-Ruiz V, Martín MA, Olives AI. An Easily Built Smoking Machine for Use by Undergraduate Students in the Determination of Total Particulate Matter and Nicotine in Tobacco Smoke. J Chem Educ 2012;89:771–5. https://doi.org/10.1021/ed200664q.
dc.identifier.doi10.1021/ed200664q
dc.identifier.essn1938-1328
dc.identifier.issn0021-9584
dc.identifier.officialurlhttps://doi.org/10.1021/ed200664q
dc.identifier.urihttps://hdl.handle.net/20.500.14352/99764
dc.journal.titleJournal of Chemical Education
dc.language.isoeng
dc.page.final775
dc.page.initial771
dc.relation.projectIDinfo:eu-repo/grantAgreement/UCM/77/2010
dc.rights.accessRightsrestricted access
dc.subject.cdu615:34
dc.subject.cdu615.31
dc.subject.keywordToxicology
dc.subject.keywordSecond-Year Undergraduate
dc.subject.keywordUpper-Division Undergraduate
dc.subject.keywordAnalytical Chemistry
dc.subject.keywordLaboratory Instruction
dc.subject.keywordHands-On Learning/Manipulatives
dc.subject.keywordConsumer Chemistry
dc.subject.keywordGas Chromatography
dc.subject.keywordLaboratory Equipment/Apparatus
dc.subject.keywordThin Layer Chromatography
dc.subject.ucmQuímica farmaceútica
dc.subject.unesco2301 Química Analítica
dc.titleAn Easily Built Smoking Machine for Use by Undergraduate Students in the Determination of Total Particulate Matter and Nicotine in Tobacco Smoke
dc.typejournal article
dc.type.hasVersionAM
dc.volume.number89
dspace.entity.typePublication
relation.isAuthorOfPublication711c3146-caca-4061-9626-60a946a50f20
relation.isAuthorOfPublication109c167c-4d5d-41f6-be94-4ca6160136a5
relation.isAuthorOfPublication.latestForDiscovery711c3146-caca-4061-9626-60a946a50f20
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